Gliclazide NEW
| Price | Get Latest Price |
| Package | 1kg |
| Min. Order: | 1kg |
| Supply Ability: | 20tons |
| Update Time: | 2024-04-05 |
Product Details
| Product Name: Gliclazide | CAS No.: 21187-98-4 |
| EC-No.: 244-260-5 | Min. Order: 1kg |
| Purity: 99% | Supply Ability: 20tons |
| Release date: 2024/04/05 |
Gliclazide is a 2nd generation oral sulfonylurea hypoglycemic agent with strong action. Its mechanism is similar to that of toluenosulfonylurea, i.e., it selectively acts on pancreatic β-cells to promote insulin secretion and enhance insulin release after eating glucose, which can not only improve the metabolism of diabetic patients, but also improve or delay the occurrence of diabetic vascular complications.
Gliclazide is mainly used for mild and moderate type II diabetes mellitus with adult-onset where diet and exercise control alone are ineffective and without a tendency to ketosis, and also improves fundus lesions and metabolic and vascular dysfunctions in diabetic patients.
| Test | Specifications | Results of analysis |
| Appearance | White or almost white powder. | White powder |
| Solubility | Practically insoluble in water; freely soluble in methylene chloride; sparingly soluble in acetone; slightly soluble in ethanol(96 percent). | Meets the requirements |
| Identifications | The infrared absorption spectrum is concordant with that obtained with gliclazide CRS. | Meets the requirements |
| Impurity B (By HPLC) | ≤2ppm | 0.5ppm |
| Heavy metals | ≤10ppm | <10ppm |
| Related substances (By HPLC) | Impurity F ≤0.1% | Non-detected |
| Each unspecified impurity ≤0.10% | 0.04% | |
| Sum of impurities other than F ≤0.2% | 0.11% | |
| Loss on drying | ≤0.25% | 0.11% |
| Sulfated ash | ≤0.1% | 0.03% |
| Residual solvents (By GC) | Ethyl acetate NMT 2500 ppm | 265ppm |
| N,N-Dimethylformamide NMT 880 ppm | Non-detected | |
| Assay | 99.0-101.0%, on dried basis. | 100.0% |
Company Profile Introduction
Shaanxi TNJONE Pharmaceutical Co., Ltd supplies more than 2,000 kinds of products, covering the whole field of health industry, including human APIs, veterinary APIs, food additives, natural nutrition ingredients, feed additives, cosmetic additives, intermediates etc. With global sourcing advantages, the group is fully capable of meeting the one-stop sourcing needs of global customers. Today, Shaanxi TNJONE Pharmaceutical Co., Ltd.'s marketing network has spread over more than 100 countries and regions on five continents, providing professional service for global customers.
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