Baicalein

Price	$1
Package	1KG

Product Details

Product Name: Baicalein	CAS No.: 491-67-8
Min. Order: 1G	Purity: 98%
Supply Ability: 100KG	Release date: 2019/07/06

AD68

Baicalein Basic information

Product Name:	Baicalein
Synonyms:	BAICALEIN(SH)NOW RG GRADE;Baicalein, monohydrate, 5,6,7-Trihydroxy-2-phenyl-4H-chromen-4-one monohydrate;Baicelein;Noroxylin;5,6,7-trihydroxy-2-phenyl-4H-chroMen-4-one;Baicalein 98%;5,6,7-trihydroxy-2-phenyl-4-chromenone hydrate;5,6,7-trihydroxy-2-phenyl-chromen-4-one hydrate
CAS:	491-67-8
MF:	C15H10O5
MW:	270.24
EINECS:
Product Categories:	Aromatics;Heterocycles;API;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;natural product;Tri-substituted Flavones;The group of Scutellaria;Inhibitors
Mol File:	491-67-8.mol

Baicalein Chemical Properties

Melting point	256-271 °C(lit.)
Boiling point	373.35°C (rough estimate)
density	1.3280 (rough estimate)
refractive index	1.5000 (estimate)
storage temp.	2-8°C
Merck	14,942
BRN	272683
CAS DataBase Reference	491-67-8(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	36/37/38-20/21/22
Safety Statements	26-36
WGK Germany	3
RTECS	DJ3100898
Hazard Note	Irritant

Baicalein Usage And Synthesis

Chemical Properties	Yellow Crystalline Solid
Uses	antiviral (HIV)
Uses	An inhibitor of 12-lipoxygenase, leukotriene biosynthesis and release of lysosomal enzymes. It also inhibits cellular Ca2+ uptake and mobilization and adjuvant-induced arthritis. Baicalein is the fl avonoid component of Nepalese and Sino-Japanese crude drugs.
Uses	inhibitor of lipoxidase and leukotriene biosynthesis
Uses	An inhibitor of Ca2+ uptake, 5-LO, and 12-LO
Definition	ChEBI: A trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7.
Uses	Baicalein is a flavonoid originally isolated from the roots of Scutellaria baicalensis Georgi. Several different functions of baicalein have been reported. Platelet 12-lipoxygenase is inhibited by baicalein with an ID50 value of 0.12 μM, with minimal inhibition of platelet cyclooxygenase-1 (IC50 = 0.83 mM). Baicalein inhibits lipid peroxidation, as assessed by production of TBARS, with an IC50 value of 5 μM. In addition to these effects, baicalein may play a role in apoptosis, as the compound inhibits cell growth of three human hepatocellular carcinoma cell lines with IC50 values ranging from 17-70 μg/ml.
Biological Activity	Inhibitor of 5- and platelet 12-lipoxygenases (IC 50 values are 9.5 and 0.12 mM respectively). Also inhibits Raf-mediated MEK-1 phosphorylation in C6 rat glioma cells and induces G1 and G2 cell cycle arrest by decreasing cdk1, cdk2, cyclin D2 and cyclin A expression. Anti-inflammatory in vivo .

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates： Pharmaceutical intermediates; OLED intermediates;

Recommended supplier

Product name	Price		Suppliers	Update time
Baicalein	$0.00/1kg	VIP1Y	BINBO BIOLOGICAL CO.,LTD	2024-03-28
baicalein	$0.00/1Kg	VIP1Y	airuikechemical co., ltd.	2024-03-27
Baicalein	$100.00/1bag		Hebei Fengqiang Trading Co., LTD	2023-08-22
Baicalein	$0.00/20kg	VIP1Y	Wuhan Haorong Biotechnology Co.,Ltd	2023-08-15
Baicalein	$0.00/1kg	VIP1Y	Hebei Yibangte Import and Export Co. , Ltd.	2023-05-25
Baicalein	$0.00/1kg	VIP3Y	Changsha Staherb Natural Ingredients Co., Ltd.	2022-04-14
Baicalein	$1.00/1kg		Wuhan Dujiang Industrial Co., Ltd.	2022-03-14
Baicalein	$15.00/1KG		Zhuozhou Wenxi import and Export Co., Ltd	2021-08-11
Baicalein	$10.50/1KG	VIP3Y	Hebei Guanlang Biotechnology Co,.LTD	2021-07-08
Baicalein	$0.00/1Kg/Bag	VIP3Y	WUHAN FORTUNA CHEMICAL CO., LTD	2021-06-04

Product Details

Company Profile Introduction

You may like

Recommended supplier

career henan chemical co