What is mannitol used for?

Mannitol injection is used to lower pressure in the head (intracranial pressure) and increased pressure in the eye (intraocular pressure). It is also used to treat swelling of the brain (cerebral edema).

What is mannitol used for?

Mannitol has the effect of reducing intracranial pressure. Lowering intracranial pressure is not a simple diuretic, mainly by increasing blood osmotic pressure, allowing water in the brain tissue to enter the blood, thereby reducing cerebral edema and reducing intracranial pressure. Generally, it takes effect within 20 minutes after intravenous injection, reaches the peak within 2-3 hours, and can last for 4-6 hours.

Mannitol Side Effects

The use of mannitol may also cause hypokalemia, induce or aggravate heart failure, hematuria, renal insufficiency or even renal failure, so attention should be paid. Pay attention when using it, do not use it as a drug to prevent cerebral edema, pay attention to the faster the drip rate, the higher the plasma osmotic pressure, and the stronger the dehydration effect.

How To Use Mannitol

Mannitol is available in the form of an lnjectable solution.

Mannitol lnjectable solutions by Intravenous as single or several doses.

Contraindications of Mannitol

Mannitol is contraindicated in patients with:

1.Well-established anuria due to severe renal disease.. Severe pulmonary congestion or frank pulmonary edema.

2.Active intracranial bleeding except during craniotomy.. Severe dehydration.

3.Progressive heart failure or pulmonary congestion after institution of mannitol therapy.

4.Do not administer to patients with a known hypersensitivity to mannitol.