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Advanced Science
Advanced Science
IF:14.3
CiteScore:18.9
Articles:1602
Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.
Astrocytic ET-1 System Determines Microglia Phenotype Following Spinal Cord Injury
Published: 30 May 2025
DOI: 10.1002/advs.202507215
Bingqiang He, Si Xu, Mengdi Li, Hui Li, Shaolan Li, Li Niu, Honghua Song, Rixin Cai, Yue Zhou, Zhilong Cao, Yingjie Wang, Yongjun Wang
Bingqiang He, Si Xu, Mengdi Li, Hui Li, Shaolan Li, Li Niu, Honghua Song, Rixin Cai, Yue Zhou, Zhilong Cao, Yingjie Wang, Yongjun Wang
Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury
Published: 14 May 2025
DOI: 10.1002/advs.202500566
Xiao Zhuang, Shuang Shi, Shuo Liu, Yaqiong Jiao, Bin Huang, Yinghong Yang, Li Yang, Xinquan Yang, Hui Wang, Chunhui Liang, Dandan Song, Huaxiang Yu, Dan Zou, Qi Sun, Shu Yang, Chengqian Yin, Jian Li, Yiming Liu, Junxia Min, Fudi Wang, Yong Nian, Lutao Du, Bo Chu
Xiao Zhuang, Shuang Shi, Shuo Liu, Yaqiong Jiao, Bin Huang, Yinghong Yang, Li Yang, Xinquan Yang, Hui Wang, Chunhui Liang, Dandan Song, Huaxiang Yu, Dan Zou, Qi Sun, Shu Yang, Chengqian Yin, Jian Li, Yiming Liu, Junxia Min, Fudi Wang, Yong Nian, Lutao Du, Bo Chu
MTFR2-Mediated Fission Drives Fatty Acid and Mitochondrial Co-Transfer from Hepatic Stellate Cells to Tumor Cells Fueling Oncogenesis
Published: 14 May 2025
DOI: 10.1002/advs.202416419
La Zhang, Baoyong Zhou, Jun Yang, Cong Ren, Jing Luo, Zhenghang Li, Qiang Liu, Zuotian Huang, Zhongjun Wu, Ning Jiang
La Zhang, Baoyong Zhou, Jun Yang, Cong Ren, Jing Luo, Zhenghang Li, Qiang Liu, Zuotian Huang, Zhongjun Wu, Ning Jiang
KDM6A Deficiency Induces Myeloid Bias and Promotes CMML-Like Disease Through JAK/STAT3 Activation by Repressing SOCS3
Published: 14 May 2025
DOI: 10.1002/advs.202413091
Huiqiao Chen, Shufen Wang, Ruoyu Dong, Pinhui Yu, Tianyu Li, Liangning Hu, Mowang Wang, Zijun Qian, Hongyu Zhou, Xiaoyan Yue, Limengmeng Wang, Haowen Xiao
Huiqiao Chen, Shufen Wang, Ruoyu Dong, Pinhui Yu, Tianyu Li, Liangning Hu, Mowang Wang, Zijun Qian, Hongyu Zhou, Xiaoyan Yue, Limengmeng Wang, Haowen Xiao
CCN1 Enhances Tumor Immunosuppression through Collagen-Mediated Chemokine Secretion in Pancreatic Cancer
Published: 27 April 2025
DOI: 10.1002/advs.202500589
Hongjie Fan, Huzi Zhao, Lili Gao, Yucheng Dong, Pei Zhang, Pengfei Yu, Yunfei Ji, Zhe-Sheng Chen, Xinmiao Liang, Yang Chen
Hongjie Fan, Huzi Zhao, Lili Gao, Yucheng Dong, Pei Zhang, Pengfei Yu, Yunfei Ji, Zhe-Sheng Chen, Xinmiao Liang, Yang Chen
Glycolysis-Derived Lactate Induces ACSL4 Expression and Lactylation to Activate Ferroptosis during Intervertebral Disc Degeneration
Published: 2 April 2025
DOI: 10.1002/advs.202416149
Kaiqiang Sun, Yangyang Shi, Chen Yan, Shunmin Wang, Linhui Han, Fudong Li, Ximing Xu, Yuan Wang, Jingchuan Sun, Zijian Kang, Jiangang Shi
Kaiqiang Sun, Yangyang Shi, Chen Yan, Shunmin Wang, Linhui Han, Fudong Li, Ximing Xu, Yuan Wang, Jingchuan Sun, Zijian Kang, Jiangang Shi
Modular Calcium-Responsive and CD9-Targeted Phospholipase System Enhancing Endosomal Escape for DNA Delivery
Published: 25 February 2025
DOI: 10.1002/advs.202410815
Alexander Klipp, Christina Greitens, David Scherer, Alexander Elsener, Jean-Christophe Leroux, Michael Burger
Alexander Klipp, Christina Greitens, David Scherer, Alexander Elsener, Jean-Christophe Leroux, Michael Burger
UFMylation of NLRP3 Prevents Its Autophagic Degradation and Facilitates Inflammasome Activation
Published: 22 February 2025
DOI: 10.1002/advs.202406786
Jiongjie Jing, Fan Yang, Ke Wang, Mintian Cui, Ni Kong, Shixi Wang, Xiaoyue Qiao, Fanyu Kong, Dongyang Zhao, Jinlu Ji, Lunxian Tang, Jiaxin Gao, Yu-Sheng Cong, Deqiang Ding, Kun Chen
Jiongjie Jing, Fan Yang, Ke Wang, Mintian Cui, Ni Kong, Shixi Wang, Xiaoyue Qiao, Fanyu Kong, Dongyang Zhao, Jinlu Ji, Lunxian Tang, Jiaxin Gao, Yu-Sheng Cong, Deqiang Ding, Kun Chen
Carnosic Acid Directly Targets STING C-Terminal Tail to Improve STING-Mediated Inflammatory Diseases
Published: 18 February 2025
DOI: 10.1002/advs.202417686
Wenqing Mu, Guang Xu, Ling Li, Jincai Wen, Ye Xiu, Jia Zhao, Tingting Liu, Ziying Wei, Wei Luo, Huijie Yang, Zhixin Wu, Xiaoyan Zhan, Xiaohe Xiao, Zhaofang Bai
Wenqing Mu, Guang Xu, Ling Li, Jincai Wen, Ye Xiu, Jia Zhao, Tingting Liu, Ziying Wei, Wei Luo, Huijie Yang, Zhixin Wu, Xiaoyan Zhan, Xiaohe Xiao, Zhaofang Bai
Identification of a Novel Substrate for eEF2K and the AURKA-SOX8 as the Related Pathway in TNBC
Published: 14 February 2025
DOI: 10.1002/advs.202412985
Xiaoya Wan, Rong Gong, Xiaobao Zhao, Yizhi Li, Tianjiao Shan, Changxin Zhong, Rongfeng Zhu, Zonglin Chen, Shilong Jiang, Linhao He, Shijun Cao, Sheng Tian, Jinming Yang, Na Ye, Wenjun Yi, Yan Cheng
Xiaoya Wan, Rong Gong, Xiaobao Zhao, Yizhi Li, Tianjiao Shan, Changxin Zhong, Rongfeng Zhu, Zonglin Chen, Shilong Jiang, Linhao He, Shijun Cao, Sheng Tian, Jinming Yang, Na Ye, Wenjun Yi, Yan Cheng
Single-Molecule Insight Into α-Synuclein Fibril Structure and Mechanics Modulated by Chemical Compounds
Published: 14 February 2025
DOI: 10.1002/advs.202416721
Xiang Li, Lulu Bi, Shenqing Zhang, Qianhui Xu, Wencheng Xia, Youqi Tao, Shaojuan Wu, Yanan Li, Weidong Le, Wenyan Kang, Dan Li, Bo Sun, Cong Liu
Xiang Li, Lulu Bi, Shenqing Zhang, Qianhui Xu, Wencheng Xia, Youqi Tao, Shaojuan Wu, Yanan Li, Weidong Le, Wenyan Kang, Dan Li, Bo Sun, Cong Liu
Ribonuclease 1 Induces T-Cell Dysfunction and Impairs CD8+ T-Cell Cytotoxicity to Benefit Tumor Growth through Hijacking STAT1
Published: 11 February 2025
DOI:
Wen-Hao Yang, Bao-Yue Huang, Hsing-Yu Rao, Peng Ye, Bi Chen, Hao-Ching Wang, Chih-Hung Chung, Heng-Hsiung Wu, Hung-Rong Yen, Shao-Chun Wang, Jong-Ho Cha, Xiuwen Yan, Muh-Hwa Yang, Mien-Chie Hung
Wen-Hao Yang, Bao-Yue Huang, Hsing-Yu Rao, Peng Ye, Bi Chen, Hao-Ching Wang, Chih-Hung Chung, Heng-Hsiung Wu, Hung-Rong Yen, Shao-Chun Wang, Jong-Ho Cha, Xiuwen Yan, Muh-Hwa Yang, Mien-Chie Hung
GNE-317 Reverses MSN-Mediated Proneural-to-Mesenchymal Transition and Suppresses Chemoradiotherapy Resistance in Glioblastoma via PI3K/mTOR.
Published: 7 February 2025
DOI: 10.1002/advs.202412517
Yong-Chang Yang, Xing-Yu Jin, Ling-Ling Yang, Xing Xu, Yang Xie, Yi-Ding Ai, Xin-Chao Li, Ye-Cheng Ma, Cheng-Long Xu, Qi Li, Xiang-Lian Ge, Tai-Long Yi, Tao Jiang, Xiao-Guang Wang, Ying-Zhe Piao, Xun Jin
Yong-Chang Yang, Xing-Yu Jin, Ling-Ling Yang, Xing Xu, Yang Xie, Yi-Ding Ai, Xin-Chao Li, Ye-Cheng Ma, Cheng-Long Xu, Qi Li, Xiang-Lian Ge, Tai-Long Yi, Tao Jiang, Xiao-Guang Wang, Ying-Zhe Piao, Xun Jin
3‐HKA Promotes Vascular Remodeling After Stroke by Modulating the Activation of A1/A2 Reactive Astrocytes
Published: 24 January 2025
DOI: 10.1002/advs.202412667
Jun-Min Chen, Guang Shi, Lu-Lu Yu, Wei Shan, Jing-Yu Sun, An-Chen Guo, Jian-Ping Wu, Tie-Shan Tang, Xiang-Jian Zhang, Qun Wang
Jun-Min Chen, Guang Shi, Lu-Lu Yu, Wei Shan, Jing-Yu Sun, An-Chen Guo, Jian-Ping Wu, Tie-Shan Tang, Xiang-Jian Zhang, Qun Wang
Targeting TTK Inhibits Tumorigenesis of T-Cell Lymphoma Through Dephosphorylating p38α and Activating AMPK/mTOR Pathway.
Published: 21 January 2025
DOI: 10.1002/advs.202413990
Bingyu Liu, Tiange Lu, Mengfei Ding, Xiaoli Zhou, Yujie Jiang, Juanjuan Shang, Wenyue Sun, Shunfeng Hu, Xin Wang, Xiangxiang Zhou
Bingyu Liu, Tiange Lu, Mengfei Ding, Xiaoli Zhou, Yujie Jiang, Juanjuan Shang, Wenyue Sun, Shunfeng Hu, Xin Wang, Xiangxiang Zhou
Liver-Secreted Extracellular Vesicles Promote Cirrhosis-Associated Skeletal Muscle Injury Through mtDNA-cGAS/STING Axis
Published: 13 January 2025
DOI: 10.1002/advs.202410439
Xiaoli Fan, Yunke Peng, Bo Li, Xiaoze Wang, Yifeng Liu, Yi Shen, Guofeng Liu, Yanyi Zheng, Qiaoyu Deng, Jingping Liu, Li Yang
Xiaoli Fan, Yunke Peng, Bo Li, Xiaoze Wang, Yifeng Liu, Yi Shen, Guofeng Liu, Yanyi Zheng, Qiaoyu Deng, Jingping Liu, Li Yang
In Situ Modulation of NiFeOOH Coordination Environment for Enhanced Electrocatalytic‐Conversion of Glucose and Energy‐Efficient Hydrogen Production
Published: 11 December 2024
DOI: 10.1002/advs.202412872
Ning Wei, Sufeng Zhang, Xue Yao, Qinglu Li, Nan Li, Jinrui Li, Dingjie Pan, Qiming Liu, Shaowei Chen, Scott Renneckar
Ning Wei, Sufeng Zhang, Xue Yao, Qinglu Li, Nan Li, Jinrui Li, Dingjie Pan, Qiming Liu, Shaowei Chen, Scott Renneckar
Triplet Electron Exchange in Carbon Nanodots‐assisted Long‐persistent near‐infrared Chemiluminescence for Oncology Synergistic Imaging and Therapy
Published: 11 December 2024
DOI: 10.1002/advs.202411898
Run-Wei Song, Tian-Ci Jiang, Xue-Yang Zhang, Cheng-Long Shen, Qing Lou, Chong-Xin Shan
Run-Wei Song, Tian-Ci Jiang, Xue-Yang Zhang, Cheng-Long Shen, Qing Lou, Chong-Xin Shan
Tumor Microenvironment‐Responsive Nanoparticles Enhance IDO1 Blockade Immunotherapy by Remodeling Metabolic Immunosuppression
Published: 11 December 2024
DOI: 10.1002/advs.202405845
Mengna Wang, Yuhong Liu, Yanshi Li, Tao Lu, Min Wang, Zhaobo Cheng, Lin Chen, Tongling Wen, Min Pan, Guohua Hu
Mengna Wang, Yuhong Liu, Yanshi Li, Tao Lu, Min Wang, Zhaobo Cheng, Lin Chen, Tongling Wen, Min Pan, Guohua Hu
CDC20-Mediated Selective Autophagy Degradation of PBRM1 Affects Immunotherapy for Renal Cell Carcinoma.
Published: 10 December 2024
DOI: 10.1002/advs.202412967
Yizeng Fan, Weichao Dan, Taotao Que, Yi Wei, Bo Liu, Zixi Wang, Yulin Zhang, Yuzhao Wang, Tianjie Liu, Yanxin Zhuang, Mengxing Li, Chendong Guo, Jin Zeng, Bohan Ma, Lei Li
Yizeng Fan, Weichao Dan, Taotao Que, Yi Wei, Bo Liu, Zixi Wang, Yulin Zhang, Yuzhao Wang, Tianjie Liu, Yanxin Zhuang, Mengxing Li, Chendong Guo, Jin Zeng, Bohan Ma, Lei Li