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Advanced Science

IF:14.3 CiteScore:18.9 Articles:1602

Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.

Targeting KIFC1 Promotes Senescence in Soft Tissue Sarcoma via FXR1-Dependent Regulation of MAD2L1 mRNA Stability

Published: 10 October 2024 DOI: 10.1002/advs.202405611
Xiu-Xia Lu, Yi Que, Jing Yang, Li-Yuan Le, Qi-Yan Cai, Bu-Shu Xu, Dong-Chun Hong, Yao Liang, Xing Zhang

Enhanced Tumor‐Targeted Delivery of Arginine‐Rich Peptides via a Positive Feedback Loop Orchestrated by Piezo1/integrin β1 Signaling Axis

Published: 11 September 2024 DOI: 10.1002/advs.202409081
Minghai Ma, Xing Li, Minxuan Jing, Pu Zhang, Mengzhao Zhang, Lu Wang, Xiao Liang, Yunzhong Jiang, Jianpeng Li, Jiale He, Xinyang Wang, Min Lin, Lei Wang, Jinhai Fan

Zosuquidar Promotes Antitumor Immunity by Inducing Autophagic Degradation of PD-L1

Published: 4 September 2024 DOI:
Ling Ding, Hongjie Guo, Jie Zhang, Mingming Zheng, Wenjie Zhang, Longsheng Wang, Qianqian Du, Chen Zhou, Yanjun Xu, Honghai Wu, Qiaojun He, Bo Yang

NEMO-Binding Domain/IKKγ Inhibitory Peptide Alleviates Neuronal Pyroptosis in Spinal Cord Injury by Inhibiting ASMase-Induced Lysosome Membrane Permeabilization

Published: 3 September 2024 DOI: 10.1002/advs.202405759
Yibo Geng, Junsheng Lou, Junnan Wu, Zhichao Tao, Ningning Yang, Jiaxuan Kuang, Yuzhe Wu, Jiacheng Zhang, Linyi Xiang, Jingwei Shi, Yuepiao Cai, Xiangyang Wang, Jiaoxiang Chen, Jian Xiao, Kailiang Zhou

Platelet-Derived Growth Factor C Facilitates Malignant Behavior of Pancreatic Ductal Adenocarcinoma by Regulating SREBP1 Mediated Lipid Metabolism

Published: 3 September 2024 DOI:
Yin-Hao Shi, Zhi-De Liu, Ming-Jian Ma, Guang-Yin Zhao, Ying-Qin Zhu, Jie-Qin Wang, Yang-Yin-Hui Yu, Xi-Tai Huang, Jing-Yuan Ye, Fu-Xi Li, Xi-Yu Wang, Qiong-Cong Xu, Xiao-Yu Yin

The Hemagglutinin of Influenza A Virus Induces Ferroptosis to Facilitate Viral Replication.

Published: 19 August 2024 DOI: 10.1002/advs.202404365
Aotian Ouyang, Tong Chen, Yi Feng, Jiahui Zou, Shaoyu Tu, Meijun Jiang, Huimin Sun, Hongbo Zhou

Polyamine Anabolism Promotes Chemotherapy-Induced Breast Cancer Stem Cell Enrichment

Published: 26 July 2024 DOI: 10.1002/advs.202404853
Guangyu Ji, Jia Liu, Zhiqun Zhao, Jie Lan, You Yang, Zheng Wang, Huijing Feng, Kai Ji, Xiaofeng Jiang, Huize Xia, Guangyao Wei, Yajing Zhang, Yuhong Zhang, Xinlong Du, Yawen Wang, Yuanyuan Yang, Zhaojian Liu, Kai Zhang, Qi Mei, Rong Sun, Haiquan Lu

Inactivated cGAS‐STING Signaling Facilitates Endocrine Resistance by Forming a Positive Feedback Loop with AKT Kinase in ER+HER2– Breast Cancer

Published: 18 July 2024 DOI: 10.1002/advs.202403592
Kai-Ming Zhang, De-Chang Zhao, Ze-Yu Li, Yan Wang, Jian-Nan Liu, Tian Du, Ling Zhou, Yu-Hong Chen, Qi-Chao Yu, Qing-Shan Chen, Rui-Zhao Cai, Zi-Xuan Zhao, Jia-Lu Shan, Bing-Xin Hu, Hai-Liang Zhang, Gong-Kan Feng, Xiao-Feng Zhu, Jun Tang, Rong Deng

Obstructive Sleep Apnea Syndrome Exacerbates NASH Progression via Selective Autophagy-Mediated Eepd1 Degradation

Published: 25 June 2024 DOI:
Jie Xiong, Ying Xu, Ning Wang, Shengming Wang, Yao Zhang, Sijia Lu, Xiaoman Zhang, Xingxing Liang, Chuchu Liu, Quanxin Jiang, Junting Xu, Qiqi Qian, Peihui Zhou, Limin Yin, Feng Liu, Suzhen Chen, Shankai Yin, Junli Liu

Picrasidine S Induces cGAS-Mediated Cellular Immune Response as a Novel Vaccine Adjuvant

Published: 20 June 2024 DOI:
Xiaofan Ding, Mengxue Sun, Fusheng Guo, Xinmin Qian, Haoyu Yuan, Wenjiao Lou, Qixuan Wang, Xiaoguang Lei, Wenwen Zeng

Biomimetic Hydrogel-Mediated Mechano-Immunometabolic Therapy for Inhibition of ccRCC Recurrence After Surgery.

Published: 17 June 2024 DOI: 10.1002/advs.202308734
Yunze Dong, Jun Luo, Mingliang Pei, Shuai Liu, Yuchen Gao, Hongmin Zhou, Yimingniyizi Nueraihemaiti, Xiangcheng Zhan, Tiancheng Xie, Xudong Yao, Xin Guan, Yunfei Xu

A Novel Ubiquitin Ligase Adaptor PTPRN Suppresses Seizure Susceptibility through Endocytosis of Na V 1.2 Sodium Channels.

Published: 14 June 2024 DOI: 10.1002/advs.202400560
Yifan Wang, Hui Yang, Na Li, Lili Wang, Chang Guo, Weining Ma, Shiqi Liu, Chao Peng, Jiexin Chen, Huifang Song, Hedan Chen, Xinyue Ma, Jingyun Yi, Jingjing Lian, Weikaixin Kong, Jie Dong, Xinyu Tu, Mala Shah, Xin Tian, Zhuo Huang

CD147-K148me2-Driven Tumor Cell-Macrophage Crosstalk Provokes NSCLC Immunosuppression via the CCL5/CCR5 Axis.

Published: 14 June 2024 DOI:
Ke Wang, Xiaohong Chen, Peng Lin, Jiao Wu, Qiang Huang, Zhi-Nan Chen, Jiale Tian, Hao Wang, Ye Tian, Mingyan Shi, Meirui Qian, Bengang Hui, Yumeng Zhu, Ling Li, Rui Yao, Huijie Bian, Ping Zhu, Ruo Chen, Liang Chen

Degradation‐Based Protein Profiling: A Case Study of Celastrol

Published: 25 April 2024 DOI: 10.1002/advs.202308186
Zhihao Ni, Yi Shi, Qianlong Liu, Liguo Wang, Xiuyun Sun, Yu Rao

Mgp High‐Expressing MSCs Orchestrate the Osteoimmune Microenvironment of Collagen/Nanohydroxyapatite‐Mediated Bone Regeneration

Published: 8 April 2024 DOI: 10.1002/advs.202308986
Zhuqing Wan, Xiaoqiang Bai, Xin Wang, Xiaodong Guo, Xu Wang, Mo Zhai, Yang Fu, Yunsong Liu, Ping Zhang, Xiao Zhang, Ruili Yang, Yan Liu, Longwei Lv, Yongsheng Zhou

Cutaneous Calcium/Calmodulin-Dependent Protein Kinase II-γ–Positive Sympathetic Nerves Secreting Norepinephrine Dictate Psoriasis

Published: 28 March 2024 DOI:
Yafen Yu, Weiwei Chen, Bao Li, Zhuo Li, Yirui Wang, Yiwen Mao, Wencheng Fan, Yuanming Bai, Hongbo Hu, Qi Zhen, Liangdan Sun

Pregnane X Receptor Activation in Liver Macrophages Protects against Endotoxin-Induced Liver Injury

Published: 13 March 2024 DOI: 10.1002/advs.202308771
Tingting Zhao, Guoping Zhong, Ying Wang, Renjie Cao, Shaofei Song, Yuan Li, Guohui Wan, Haiyan Sun, Min Huang, Huichang Bi, Yiming Jiang

A Single-Atom Manganese Nanozyme Mn-N/C Promotes Anti-Tumor Immune Response via Eliciting Type I Interferon Signaling

Published: 2 February 2024 DOI: 10.1002/advs.202305979
Wen Qiao, Jingqi Chen, Huayuan Zhou, Cegui Hu, Sumiya Dalangood, Hanjun Li, Dandan Yang, Yu Yang, Jun Gui

Design and Characterization of a Novel eEF2K Degrader with Potent Therapeutic Efficacy Against Triple-Negative Breast Cancer

Published: 12 December 2023 DOI:
Changxin Zhong, Rongfeng Zhu, Ting Jiang, Sheng Tian, Xiaobao Zhao, Xiaoya Wan, Shilong Jiang, Zonglin Chen, Rong Gong, Linhao He, Jin-Ming Yang, Na Ye, Yan Cheng

G3BP1 and SLU7 Jointly Promote Immune Evasion by Downregulating MHC‐I via PI3K/Akt Activation in Bladder Cancer

Published: 12 December 2023 DOI: 10.1002/advs.202305922
Xianchong Zheng, Jiawei Chen, Minhua Deng, Kang Ning, Yulu Peng, Zhenhua Liu, Xiangdong Li, Zhaohui Zhou, Huancheng Tang, Yaoying Li, Tiebang Kang, Zhuowei Liu

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