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Advanced Science

IF:14.3 CiteScore:18.9 Articles:1602

Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.

Metabolic Enzyme SLC27A5 Regulates PIP4K2A pre-mRNA Splicing as a Noncanonical Mechanism to Suppress Hepatocellular Carcinoma Metastasis

Published: 7 December 2023 DOI:
Dan Nie, Xin Tang, Haijun Deng, Xiaojun Yang, Junji Tao, Fengli Xu, Yi Liu, Kang Wu, Kai Wang, Zhechuan Mei, Ailong Huang, Ni Tang

Regeneration of Thyroid Glands in the Spleen Restores Homeostasis in Thyroidectomy Mice

Published: 7 December 2023 DOI: 10.1002/advs.202305913
Xue-Jiao Tian, Zhi-Jie Yin, Zhen-Jiang Li, Zhen-Zhen Wang, Zhen Xing, Chun-Yan Liu, Lin-Tao Wang, Chun-Ming Wang, Jun-Feng Zhang, Lei Dong

HSPA8 Activates Wnt/β-Catenin Signaling to Facilitate BRAF V600E Colorectal Cancer Progression by CMA-Mediated CAV1 Degradation.

Published: 16 November 2023 DOI: 10.1002/advs.202306535
Bowen Li, Hui Ming, Siyuan Qin, Li Zhou, Zhao Huang, Ping Jin, Liyuan Peng, Maochao Luo, Tingting Zhang, Kui Wang, Rui Liu, Yih-Cherng Liou, Edouard C. Nice, Jingwen Jiang, Canhua Huang

Medical Gas Plasma Technology Combines with Antimelanoma Therapies and Promotes Immune-Checkpoint Therapy Responses.

Published: 4 August 2023 DOI: 10.1002/advs.202303183
Lea Miebach, Gabriella Melo-Zainzinger, Eric Freund, Ramona Clemen, Alessandra Lourenco Cecchini, Sander Bekeschus

A Mosaic Nanoparticle Vaccine Elicits Potent Mucosal Immune Response with Significant Cross-Protection Activity against Multiple SARS-CoV-2 Sublineages.

Published: 1 August 2023 DOI: 10.1002/advs.202301034
Xiantao Zhang, Shijian Wu, Jie Liu, Ran Chen, Yongli Zhang, Yingtong Lin, Zhihui Xi, Jieyi Deng, Zeyu Pu, Chaofeng Liang, Jinzhu Feng, Rong Li, Keming Lin, Mo Zhou, Yingying Liu, Xu Zhang, Bingfeng Liu, Yiwen Zhang, Xin He, Hui Zhang

MSCs Deliver Hypoxia‐Treated Mitochondria Reprogramming Acinar Metabolism to Alleviate Severe Acute Pancreatitis Injury

Published: 6 July 2023 DOI: 10.1002/advs.202207691
Zhengyu Hu, Dongyan Wang, Jian Gong, Yan Li, Zhilong Ma, Tingyi Luo, Xuyang Jia, Yihai Shi, Zhenshun Song

Donafenib and GSK??J4 Synergistically Induce Ferroptosis in Liver Cancer by Upregulating HMOX1 Expression

Published: 17 June 2023 DOI: 10.1002/advs.202206798
Chenyang Zheng, Bo Zhang, Yunyun Li, Kejia Liu, Wei Wei, Shuhang Liang, Hongrui Guo, Kun Ma, Yao Liu, Jiabei Wang, Lianxin Liu

A Dendrimer Peptide (KK2DP7) Delivery System with Dual Functions of Lymph Node Targeting and Immune Adjuvants as a General Strategy for Cancer Immunotherapy

Published: 22 March 2023 DOI: 10.1002/advs.202300116
Rui Zhang, Lin Tang, Yusi Wang, Yaomei Tian, Siwen Wu, Bailing Zhou, Chunyan Dong, Binyan Zhao, Yuling Yang, Daoyuan Xie, Li Yang

Suppressing Mesenchymal Stromal Cell Ferroptosis Via Targeting a Metabolism-Epigenetics Axis Corrects their Poor Retention and Insufficient Healing Benefits in the Injured Liver Milieu

Published: 19 February 2023 DOI:
Guangyu Hu, Zhe Cui, Xiyao Chen, Fangfang Sun, Tongzheng Li, Congye Li, Ling Zhang, Xiong Guo, Hang Zhao, Yunlong Xia, Wenjun Yan, Wei Yi, Miaomiao Fan, Rongjin Yang, Shan Wang, Ling Tao, Fuyang Zhang

Tryptophan Metabolism Acts as a New Anti-Ferroptotic Pathway to Mediate Tumor Growth.

Published: 10 January 2023 DOI: 10.1002/advs.202204006
Dong Liu, Chun-hui Liang, Bin Huang, Xiao Zhuang, Weiwei Cui, Li Yang, Yinghong Yang, Yudan Zhang, Xiaolong Fu, Xiaoju Zhang, Lutao Du, Wei Gu, Xiangdong Wang, Chengqian Yin, Renjie Chai, Bo Chu

RNF126‐Mediated MRE11 Ubiquitination Activates the DNA Damage Response and Confers Resistance of Triple‐Negative Breast Cancer to Radiotherapy

Published: 23 December 2022 DOI: 10.1002/advs.202203884
Wenjing Liu, Min Zheng, Rou Zhang, Qiuyun Jiang, Guangshi Du, Yingying Wu, Chuanyu Yang, Fubing Li, Wei Li, Luzhen Wang, Jiao Wu, Lei Shi, Wenhui Li, Kai Zhang, Zhongmei Zhou, Rong Liu, Yingzheng Gao, Xinwei Huang, Songqing Fan, Xu Zhi, Dewei Jiang, Ceshi Chen

Metabolic Rewiring of Kynurenine Pathway during Hepatic Ischemia–Reperfusion Injury Exacerbates Liver Damage by Impairing NAD Homeostasis

Published: 30 October 2022 DOI: 10.1002/advs.202204697
Bowen Xu, Peng Zhang, Xiaolong Tang, Shiguan Wang, Jing Shen, Yuanwen Zheng, Chao Gao, Ping Mi, Cuijuan Zhang, Hui Qu, Shiyang Li, Detian Yuan

Geometric Constraints Regulate Energy Metabolism and Cellular Contractility in Vascular Smooth Muscle Cells by Coordinating Mitochondrial DNA Methylation

Published: 14 September 2022 DOI: 10.1002/advs.202203995
Han Liu, Yuefeng Liu, He Wang, Qiang Zhao, Tao Zhang, Si-an Xie, Yueqi Liu, Yuanjun Tang, Qin Peng, Wei Pang, Weijuan Yao, Jing Zhou

Investigating and Resolving Cardiotoxicity Induced by COVID-19 Treatments using Human Pluripotent Stem Cell-Derived Cardiomyocytes and Engineered Heart Tissues

Published: 2 September 2022 DOI: 10.1002/advs.202203388
He Xu, Ge Liu, Jixing Gong, Ying Zhang, Shanshan Gu, Zhongjun Wan, Pengcheng Yang, Yage Nie, Yinghan Wang, Zhan-peng Huang, Guanzheng Luo, Zhongyan Chen, Donghui Zhang, Nan Cao

Microglia Regulate Blood–Brain Barrier Integrity via MiR‐126a‐5p/MMP9 Axis during Inflammatory Demyelination, Microglia Regulate Blood–Brain Barrier Integrity via MiR‐126a‐5p/MMP9 Axis during Inflammatory Demyelination

Published: 27 June 2022 DOI: 10.1002/advs.202105442
Zhongwang Yu, Xue Fang, Weili Liu, Rui Sun, Jintao Zhou, Yingyan Pu, Ming Zhao, Dingya Sun, Zhenghua Xiang, Peng Liu, Yuqiang Ding, Li Cao, Cheng He

Functional Immune Cell‐Derived Exosomes Engineered for the Trilogy of Radiotherapy Sensitization, Functional Immune Cell‐Derived Exosomes Engineered for the Trilogy of Radiotherapy Sensitization

Published: 17 June 2022 DOI: 10.1002/advs.202106031
Xiaotu Ma, Meinan Yao, Yu Gao, Yale Yue, Yao Li, Tianjiao Zhang, Guangjun Nie, Xiao Zhao, Xiaolong Liang

A Temporal PROTAC Cocktail-Mediated Sequential Degradation of AURKA Abrogates Acute Myeloid Leukemia Stem Cells.

Published: 2 June 2022 DOI: 10.1002/advs.202104823
Fang Liu, Xuan Wang, Jianli Duan, Zhijie Hou, Zhouming Wu, Lingling Liu, Hanqi Lei, Dan Huang, Yifei Ren, Yue Wang, Xinyan Li, Junxiao Zhuo, Zijian Zhang, Bin He, Min Yan, Huiming Yuan, Lihua Zhang, Jinsong Yan, Shijun Wen, Zifeng Wang, Quentin Liu

Local Release of TGF-β Inhibitor Modulates Tumor-Associated Neutrophils and Enhances Pancreatic Cancer Response to Combined Irreversible Electroporation and Immunotherapy

Published: 7 February 2022 DOI: 10.1002/advs.202105240
Huiming Peng, Jian Shen, Xin Long, Xiaoqi Zhou, Jiaqi Zhang, Xina Xu, Teng Huang, Hui Xu, Shuguo Sun, Chun Li, Ping Lei, Heshui Wu, Jun Zhao

A Novel Mechanism of Endoplasmic Reticulum Stress- and c-Myc-Degradation-Mediated Therapeutic Benefits of Antineurokinin-1 Receptor Drugs in Colorectal Cancer

Published: 3 October 2021 DOI: 10.1002/advs.202101936
Yue Shi, Xi Wang, Yueming Meng, Junjie Ma, Qiyu Zhang, Gang Shao, Lingfei Wang, Xurui Cheng, Xiangyu Hong, Yong Wang, Zhibin Yan, Yihai Cao, Jian Kang, Caiyun Fu

DDIT4 S-Nitrosylation Aids p38-MAPK Signaling Complex Assembly to Promote Hepatic Reactive Oxygen Species Production

Published: 26 July 2021 DOI: 10.1002/advs.202101957
Zilong Li, Qianwen Zhao, Yunjie Lu, Yangxi Zhang, Luyang Li, Min Li, Xuemin Chen, Donglin Sun, Yunfei Duan, Yong Xu

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