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Scientific Reports
Scientific Reports
IF:3.8
CiteScore:7.5
Articles:19567
We publish original research from all areas of the natural sciences, psychology, medicine and engineering. You can learn more about what we publish by browsing our specific scientific subject areas below or explore Scientific Reports by browsing all articles and collections.
Scientific Reports has a 2-year impact factor: 4.380 (2021), and is the 6th most-cited journal in the world, with more than 540,000 citations in 2020 (Clarivate Analytics, 2021).
•Engineering
Engineering covers all aspects of engineering, technology, and applied science. It plays a crucial role in the development of technologies to address some of the world''s biggest challenges, helping to save lives and improve the way we live.
•Physical sciences
Physical sciences are those academic disciplines that aim to uncover the underlying laws of nature — often written in the language of mathematics. It is a collective term for areas of study including astronomy, chemistry, materials science and physics.
•Earth and environmental sciences
Earth and environmental sciences cover all aspects of Earth and planetary science and broadly encompass solid Earth processes, surface and atmospheric dynamics, Earth system history, climate and climate change, marine and freshwater systems, and ecology. It also considers the interactions between humans and these systems.
•Biological sciences
Biological sciences encompass all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and biophysics, and covers all organisms from microorganisms, animals to plants.
•Health sciences
The health sciences study health, disease and healthcare. This field of study aims to develop knowledge, interventions and technology for use in healthcare to improve the treatment of patients.
Role of ATP citrate lyase and its complementary partner on fatty acid synthesis in gastric cancer
Published: 3 December 2024
DOI: 10.1038/s41598-024-81448-1
Chunlei Li, Wenxuan Liu, Youzhao Liu, Weixing Wang, Wenhong Deng
Chunlei Li, Wenxuan Liu, Youzhao Liu, Weixing Wang, Wenhong Deng
Atorvastatin calcium alleviates UVB-induced HaCat cell senescence and skin photoaging
Published: 3 December 2024
DOI: 10.1038/s41598-024-81573-x
Man Li, Yuchen Ge, Shirui Bai, Jing Xia, Guangming Wang, Yaxuan Zhang, Yuanyuan Zhang, Xiaobo Wang, Min Zhou
Man Li, Yuchen Ge, Shirui Bai, Jing Xia, Guangming Wang, Yaxuan Zhang, Yuanyuan Zhang, Xiaobo Wang, Min Zhou
Inhibitory effect of 1,4,5,6-tetrahydroxy-7,8-diprenylxanthone against NSCLC with L858R/T790M/C797S mutant EGFR
Published: 4 November 2024
DOI: 10.1038/s41598-024-78146-3
Jing Wang, Yuna Wang, Shuanggou Zhang, Yana Qu, Ruohan Zhang, Xuanjun Wang, Jun Sheng, Peiyuan Sun
Jing Wang, Yuna Wang, Shuanggou Zhang, Yana Qu, Ruohan Zhang, Xuanjun Wang, Jun Sheng, Peiyuan Sun
Design, in silico studies and biological evaluation of novel chalcones tethered triazolo[3,4-a]isoquinoline as EGFR inhibitors targeting resistance in non-small cell lung cancer
Published: 4 November 2024
DOI: 10.1038/s41598-024-76459-x
Nesma Abdelaal, Mohamed A Ragheb, Hamdi M Hassaneen, Emad M Elzayat, Ismail A Abdelhamid
Nesma Abdelaal, Mohamed A Ragheb, Hamdi M Hassaneen, Emad M Elzayat, Ismail A Abdelhamid
Synergistic effects of bloom helicase (BLM) inhibitor AO/854 with cisplatin in prostate cancer
Published: 23 October 2024
DOI: 10.1038/s41598-024-75938-5
Xiaoyan Ma, Fu Tian, Yuanpin Xiao, Mengqiu Huang, Dandan Song, Xinlin Chen, Houqiang Xu
Xiaoyan Ma, Fu Tian, Yuanpin Xiao, Mengqiu Huang, Dandan Song, Xinlin Chen, Houqiang Xu
Genistein inhibits HIF-1α and attenuates high glucose-induced peritoneal mesothelial-mesenchymal transition and fibrosis via the mTOR/OGT pathway
Published: 17 October 2024
DOI: 10.1038/s41598-024-74879-3
Jian Wang, Xin Lv, Yao Lin, Ashanjiang Aniwan, Hongyan Liu, Saijun Zhou, Pei Yu
Jian Wang, Xin Lv, Yao Lin, Ashanjiang Aniwan, Hongyan Liu, Saijun Zhou, Pei Yu
The activation of the Notch signaling pathway by UBE2C promotes the proliferation and metastasis of hepatocellular carcinoma
Published: 1 October 2024
DOI: 10.1038/s41598-024-72714-3
Ping Zhan, Yuyan Lu, Jing Lu, Yizhe Cheng, Changhong Luo, Fan Yang, Wenqing Xi, Jinzhu Wang, Xuesong Cen, Fuqiang Wang, Chengrong Xie, Zhenyu Yin
Ping Zhan, Yuyan Lu, Jing Lu, Yizhe Cheng, Changhong Luo, Fan Yang, Wenqing Xi, Jinzhu Wang, Xuesong Cen, Fuqiang Wang, Chengrong Xie, Zhenyu Yin
Morphine promotes non-small cell lung cancer progression by downregulating E-cadherin via the PI3K/AKT/mTOR pathway
Published: 10 September 2024
DOI: 10.1038/s41598-024-72198-1
Fulei Gu, Yuxuan Zhou, Lili Tian, Jinyan Chen, Can Zhang, Zhangxiang Huang, Weifeng Yu, Kangjie Xie
Fulei Gu, Yuxuan Zhou, Lili Tian, Jinyan Chen, Can Zhang, Zhangxiang Huang, Weifeng Yu, Kangjie Xie
Protective effects of patchouli alcohol against DSS-induced ulcerative colitis
Published: 20 July 2024
DOI: 10.1038/s41598-024-66259-8
Huifang Han, Min Gao, Fanghong Wang, Zheng Luo, Xuejun Jiang, Yu Qiu, Junhao Su, Xinhao Duan, Shiyue Luo, Shixin Tang, Ahmad Khan, Zhen Zou, Chengzhi Chen, Qi Yin, Jingfu Qiu, Hongyang Zhang
Huifang Han, Min Gao, Fanghong Wang, Zheng Luo, Xuejun Jiang, Yu Qiu, Junhao Su, Xinhao Duan, Shiyue Luo, Shixin Tang, Ahmad Khan, Zhen Zou, Chengzhi Chen, Qi Yin, Jingfu Qiu, Hongyang Zhang
Empagliflozin rescues pro-arrhythmic and Ca2+ homeostatic effects of transverse aortic constriction in intact murine hearts
Published: 8 July 2024
DOI: 10.1038/s41598-024-66098-7
Qiang Wen, Rui Zhang, Kejun Ye, Jun Yang, Hangchuan Shi, Zhu Liu, Yangpeng Li, Ting Liu, Shiyu Zhang, Wanpei Chen, Jingjing Wu, Weichao Liu, Xiaoqiu Tan, Ming Lei, Christopher L-H Huang, Xianhong Ou
Qiang Wen, Rui Zhang, Kejun Ye, Jun Yang, Hangchuan Shi, Zhu Liu, Yangpeng Li, Ting Liu, Shiyu Zhang, Wanpei Chen, Jingjing Wu, Weichao Liu, Xiaoqiu Tan, Ming Lei, Christopher L-H Huang, Xianhong Ou
Combined effect of gallic acid and zinc ferrite nanoparticles on wheat growth and yield under salinity stress.
Published: 4 June 2024
DOI: 10.1038/s41598-024-63175-9
Qingqin Shao, Lantian Ren, Musarrat Ramzan, Muhammad Baqir Hussain, Rahul Datta, Hesham S Almoallim, Mohammad Javed Ansari, Abdullah Ehsan
Qingqin Shao, Lantian Ren, Musarrat Ramzan, Muhammad Baqir Hussain, Rahul Datta, Hesham S Almoallim, Mohammad Javed Ansari, Abdullah Ehsan
Sinomenine treats rheumatoid arthritis by inhibiting MMP9 and inflammatory cytokines expression: bioinformatics analysis and experimental validation
Published: 4 June 2024
DOI: 10.1038/s41598-024-61769-x
Jinfang Luo, Yi Zhu, Yang Yu, Yujie Chen, Kang He, Jianxin Liu
Jinfang Luo, Yi Zhu, Yang Yu, Yujie Chen, Kang He, Jianxin Liu
Aggregation of human osteoblasts unlocks self-reliant differentiation and constitutes a microenvironment for 3D-co-cultivation with other bone marrow cells
Published: 6 May 2024
DOI: 10.1038/s41598-024-60986-8
Sabrina Marozin, Birgit Simon-Nobbe, Astrid Huth, Evelyn Beyerer, Laurenz Weber, Andreas Nüssler, Günter Lepperdinger
Sabrina Marozin, Birgit Simon-Nobbe, Astrid Huth, Evelyn Beyerer, Laurenz Weber, Andreas Nüssler, Günter Lepperdinger
Tenovin 3 induces apoptosis and ferroptosis in EGFR 19del non small cell lung cancer cells
Published: 1 April 2024
DOI: 10.1038/s41598-024-58499-5
Sha Lv, Qianrong Pan, Weijin Lu, Weisong Zhang, Naike Wang, Lijuan Huang, Lianjing Li, Jieyao Liu, Jiamei Ma, Zhan Li, Yong Huang, Qiudi Deng, Xueping Lei
Sha Lv, Qianrong Pan, Weijin Lu, Weisong Zhang, Naike Wang, Lijuan Huang, Lianjing Li, Jieyao Liu, Jiamei Ma, Zhan Li, Yong Huang, Qiudi Deng, Xueping Lei
A bioluminescent and homogeneous assay for monitoring GPCR-mediated cAMP modulation and PDE activity
Published: 23 February 2024
DOI: 10.1038/s41598-024-55038-0
Dareen Mikheil, Matthew A Larsen, Kevin Hsiao, Nathan H Murray, Tim Ugo, Hui Wang, Said A Goueli
Dareen Mikheil, Matthew A Larsen, Kevin Hsiao, Nathan H Murray, Tim Ugo, Hui Wang, Said A Goueli
Ripa-56 protects retinal ganglion cells in glutamate-induced retinal excitotoxic model of glaucoma
Published: 15 February 2024
DOI: 10.1038/s41598-024-54075-z
Lemeng Feng, Shirui Dai, Cheng Zhang, Wulong Zhang, Weiming Zhu, Chao Wang, Ye He, Weitao Song
Lemeng Feng, Shirui Dai, Cheng Zhang, Wulong Zhang, Weiming Zhu, Chao Wang, Ye He, Weitao Song
Identification of potential inhibitor against Leishmania donovani mitochondrial DNA primase through in-silico and in vitro drug repurposing approaches
Published: 8 February 2024
DOI: 10.1038/s41598-024-53316-5
Mitul Nath, Deep Bhowmik, Satabdi Saha, Rajat Nandi, Diwakar Kumar
Mitul Nath, Deep Bhowmik, Satabdi Saha, Rajat Nandi, Diwakar Kumar
Graft-derived neurons and bystander effects are maintained for six months after human iPSC-derived NESC transplantation in mice’s cerebella
Published: 8 February 2024
DOI: 10.1038/s41598-024-53542-x
Liliana S Mendonça, Daniel Henriques, Vanessa Fernandes, Ricardo Moreira, João Brás, Sónia Duarte, Jens C Schwamborn, Luís Pereira de Almeida
Liliana S Mendonça, Daniel Henriques, Vanessa Fernandes, Ricardo Moreira, João Brás, Sónia Duarte, Jens C Schwamborn, Luís Pereira de Almeida
Inactivation of phosphodiesterase-4B gene in rat nucleus accumbens shell by CRISPR/Cas9 or positive allosteric modulation of the protein affects the motivation to chronically self-administer nicotine
Published: 31 January 2024
DOI: 10.1038/s41598-024-53037-9
Burt M. Sharp, Qin Jiang, Panjun Kim, Hao Chen
Burt M. Sharp, Qin Jiang, Panjun Kim, Hao Chen
Exploring the mechanism and phytochemicals in Psoraleae Fructus-induced hepatotoxicity based on RNA-seq, in vitro screening and molecular docking
Published: 19 January 2024
DOI: 10.1038/s41598-023-50454-0
Huiying Shang, Xian Liu, Jinchao Pan, Hongbo Cheng, Zengchun Ma, Chengrong Xiao, Yue Gao
Huiying Shang, Xian Liu, Jinchao Pan, Hongbo Cheng, Zengchun Ma, Chengrong Xiao, Yue Gao




