9-CIS-RETINOIC ACID
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- ₹9526
- Product name: 9-CIS-RETINOIC ACID
- CAS: 5300-03-8
- MF: C20H28O2
- MW: 300.44
- EINECS:1533716-785-6
- MDL Number:MFCD00270072
- Synonyms:RETINOIC ACID, 9-CIS-;RARECHEM AL BE 0738;(2E,4E,6Z,8E)-3,7-DIMETHYL-9-(2,6,6-TRIMETHYLCYCLOHEX-1-ENYL)NONA-2,4,6,8-TETRAENOIC ACID;9-CIS-RETINOIC ACID;9-CIS-TRETINOIN;9-cis-tretinoi;3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-t;ALIRETINOIN
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Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- ManufacturerSigma-Aldrich(India)
- Product numberR4643
- Product description9-cis-Retinoic acid ≥98% (HPLC)
- Packaging1MG
- Price₹9526
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | R4643 | 9-cis-Retinoic acid ≥98% (HPLC) | 1MG | ₹9526 | 2022-06-14 | Buy |
Properties
Melting point :189-191°C
Boiling point :462.8±14.0 °C(Predicted)
Density :1.011±0.06 g/cm3(Predicted)
RTECS :VH6450000
storage temp. :-20°C
solubility :Acetonitrile (Very Slightly), Chloroform (Slightly), DMSO (Slightly), Ethanol (
pka :4.73±0.33(Predicted)
form :Light yellow to orange crystalline powder.
color :Pale Yellow to Yellow
biological source :natural
Water Solubility :Soluble in chloroform (50 mg/ml), DMSO (~25 mg/ml), ethanol (25 mg/ml), and acetone (25 mg/ml). Insoluble in water.
Sensitive :Moisture & Light Sensitive
Stability :Store Dry in Freezer at -20°C for up to 1 year; in Solution at -20°C for up to 3 Months.
InChI :InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+
InChIKey :SHGAZHPCJJPHSC-ZVCIMWCZSA-N
SMILES :C(O)(=O)/C=C(/C=C/C=C(\C=C\C1C(C)(C)CCCC=1C)/C)\C
CAS DataBase Reference :5300-03-8(CAS DataBase Reference)
Boiling point :462.8±14.0 °C(Predicted)
Density :1.011±0.06 g/cm3(Predicted)
RTECS :VH6450000
storage temp. :-20°C
solubility :Acetonitrile (Very Slightly), Chloroform (Slightly), DMSO (Slightly), Ethanol (
pka :4.73±0.33(Predicted)
form :Light yellow to orange crystalline powder.
color :Pale Yellow to Yellow
biological source :natural
Water Solubility :Soluble in chloroform (50 mg/ml), DMSO (~25 mg/ml), ethanol (25 mg/ml), and acetone (25 mg/ml). Insoluble in water.
Sensitive :Moisture & Light Sensitive
Stability :Store Dry in Freezer at -20°C for up to 1 year; in Solution at -20°C for up to 3 Months.
InChI :InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+
InChIKey :SHGAZHPCJJPHSC-ZVCIMWCZSA-N
SMILES :C(O)(=O)/C=C(/C=C/C=C(\C=C\C1C(C)(C)CCCC=1C)/C)\C
CAS DataBase Reference :5300-03-8(CAS DataBase Reference)
Safety Information
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Description
9-cis-Retinoic acid is a natural metabolite of vitamin A, derived from the intermediate all-trans retinoic acid . It potently activates all isoforms of retinoic acid receptor (RAR) (Ki = 0.5-27 nM) as well as retinoid X receptor (RXR) isoforms (Ki = 3.8-12 nM). RAR heterodimerizes with RXR, while RXR can homodimerize as well as heterodimerize with numerous partners in addition to RAR, thus allowing 9-cis-retinoic acid to evoke a wide range of effects.Related product price
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