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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
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ChemicalBook >> CAS DataBase List >> AKTI-1/2

AKTI-1/2

AKTI-1/2 price.
  • $29 - $2200
  • Product name: AKTI-1/2
  • CAS: 612847-09-3
  • MF: C34H29N7O
  • MW: 551.64
  • EINECS:1592732-453-0
  • MDL Number:MFCD09026909
  • Synonyms:1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-on;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-γ],guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2H-benzimidazol-2-one;2H-BenziMidazol-2-one, 1,3-dihydro-1-[1-[[4-(6-phenyl-1H-iMidazo[4,5-g]quinoxalin-7-yl)phenyl]Methyl]-4-piperidinyl]-;AKT inhibitor VIII (AKTI-1/2);1-(1-(4-(6-Phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)benzyl)-piperidin-4-yl)-1H-benzo[d]imidazol-2(;1-(1-(4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)benzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
Price37 Properties Safety Information Description
37 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 500μg
  • 1MG
  • 2mg
  • 2.5MG
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 100mg
  • 1g
  • 10mM(in 1mL DMSO)
  • 250mg
  • ManufacturerAK Scientific
  • Product numberX2144
  • Product descriptionAKT Inhibitor VIII
  • Packaging250mg
  • Price$1454
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000362
  • Product descriptionAKTI-1/2 INHIBITOR 95.00%
  • Packaging1MG
  • Price$240.45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000362
  • Product descriptionAKTI-1/2 INHIBITOR 95.00%
  • Packaging2.5MG
  • Price$715
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000362
  • Product descriptionAKTI-1/2 INHIBITOR 95.00%
  • Packaging25MG
  • Price$1963.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3149
  • Product descriptionAKT Inhibitor VIII
  • Packaging10mM(in 1mL DMSO)
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3149
  • Product descriptionAKT Inhibitor VIII
  • Packaging10mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3149
  • Product descriptionAKT Inhibitor VIII
  • Packaging25mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2540
  • Product descriptionAktInhibitorVIII-Akti-1/2 98%
  • Packaging25mg
  • Price$368.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17246
  • Product descriptionAkti-1/2
  • Packaging1mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17246
  • Product descriptionAkti-1/2
  • Packaging2mg
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17246
  • Product descriptionAkti-1/2
  • Packaging5mg
  • Price$375
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17246
  • Product descriptionAkti-1/2
  • Packaging10mg
  • Price$570
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17246
  • Product descriptionAkti-1/2
  • Packaging25mg
  • Price$1135
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14870
  • Product descriptionAkt Inhibitor VIII ≥98%
  • Packaging500μg
  • Price$29
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14870
  • Product descriptionAkt Inhibitor VIII ≥98%
  • Packaging1mg
  • Price$55
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14870
  • Product descriptionAkt Inhibitor VIII ≥98%
  • Packaging5mg
  • Price$128
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X2144 AKT Inhibitor VIII 250mg $1454 2021-12-16 Buy
American Custom Chemicals Corporation INB0000362 AKTI-1/2 INHIBITOR 95.00% 1MG $240.45 2021-12-16 Buy
American Custom Chemicals Corporation INB0000362 AKTI-1/2 INHIBITOR 95.00% 2.5MG $715 2021-12-16 Buy
American Custom Chemicals Corporation INB0000362 AKTI-1/2 INHIBITOR 95.00% 25MG $1963.5 2021-12-16 Buy
ApexBio Technology A3149 AKT Inhibitor VIII 10mM(in 1mL DMSO) $130 2021-12-16 Buy
ApexBio Technology A3149 AKT Inhibitor VIII 10mg $145 2021-12-16 Buy
ApexBio Technology A3149 AKT Inhibitor VIII 25mg $350 2021-12-16 Buy
Axon Medchem Axon2540 AktInhibitorVIII-Akti-1/2 98% 25mg $368.5 2021-12-16 Buy
Biosynth Carbosynth FA17246 Akti-1/2 1mg $220 2021-12-16 Buy
Biosynth Carbosynth FA17246 Akti-1/2 2mg $330 2021-12-16 Buy
Biosynth Carbosynth FA17246 Akti-1/2 5mg $375 2021-12-16 Buy
Biosynth Carbosynth FA17246 Akti-1/2 10mg $570 2021-12-16 Buy
Biosynth Carbosynth FA17246 Akti-1/2 25mg $1135 2021-12-16 Buy
Cayman Chemical 14870 Akt Inhibitor VIII ≥98% 500μg $29 2024-03-01 Buy
Cayman Chemical 14870 Akt Inhibitor VIII ≥98% 1mg $55 2024-03-01 Buy
Cayman Chemical 14870 Akt Inhibitor VIII ≥98% 5mg $128 2024-03-01 Buy
Next Last

Properties

Melting point :242-245°C (dec.)
Density :1.350±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL in DMSO
pka :7.49±0.50(Predicted)
form :Yellow solid
color :White to Yellow to Orange
CAS DataBase Reference :612847-09-3

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKBα, β, γ) modulate cell proliferation, metabolism, and survival as well as angiogenesis. Akt inhibitor VIII is a potent allosteric inhibitor of Akt1 and Akt2 (IC50s = 58 and 210 nM, respectively) that less effectively blocks Akt3 activity (IC50 = 2.2 μM). It is a poor or ineffective inhibitor of a wide range of other serine-threonine kinases. Akt inhibitor VIII is cell permeable, blocking insulin regulation of forkhead box 01 activity at 1 μM in rat hepatoma cells.

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Suppliers and manufacturers

career henan chemical co
AKTI-1/2
$2.00 /1kg
AKTI-1/2 CAS:612847-09-3
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