AT9283
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- $43 - $4365.9
- Product name: AT9283
- CAS: 896466-04-9
- MF: C19H23N7O2
- MW: 381.43
- EINECS:
- MDL Number:MFCD12031513
- Synonyms:1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea AT9283;AT9283, >=98%;N-cyclopropyl-N'-[3-[5-(4-morpholinylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]Urea;Urea, N-cyclopropyl-N'-[3-[6-(4-morpholinylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]-;1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea;CS-48;AT-9283; AT 9283;J-504568
93 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
Package
- 1mg
- 2mg
- 5mg
- 2x5mg
- 10mg
- 20MG
- 25mg
- 50mg
- 2x25mg
- 100mg
- 10mM*1mLinDMSO(Solution)
- 200mg
- 250.00mg
- 10mM*1mLinDMSO
- 250mg
- 1g
- 1.00g
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM(in1mLDMSO)
- 10mM(in 1mL DMSO)
- Manufactureraablocks
- Product numberAA00366H
- Product description1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea
- Packaging2mg
- Price$48
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00366H
- Product description1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea
- Packaging5mg
- Price$79
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00366H
- Product description1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea
- Packaging10mg
- Price$116
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00366H
- Product description1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea ≥98%
- Packaging25mg
- Price$219
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00366H
- Product description1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea ≥98%
- Packaging50mg
- Price$292
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00366H
- Product description1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea
- Packaging100mg
- Price$550
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00366H
- Product description1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea
- Packaging200mg
- Price$761
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX212070
- Product descriptionAT9283 97%
- Packaging100MG
- Price$790
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX212070
- Product descriptionAT9283 97%
- Packaging20MG
- Price$280
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1011-M010
- Product descriptionAT9283 ≥95%
- Packaging10mg
- Price$270
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1011-M050
- Product descriptionAT9283 ≥95%
- Packaging50mg
- Price$799
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1011-M005
- Product descriptionAT9283 ≥95%
- Packaging5mg
- Price$162
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1011-M001
- Product descriptionAT9283 ≥95%
- Packaging1mg
- Price$86
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1011-M001
- Product descriptionAT9283 ≥95%
- Packaging1mg
- Price$86
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberX7478
- Product description1-cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea
- Packaging250mg
- Price$1887
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7478
- Product description1-cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea
- Packaging1g
- Price$4132
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00366H | 1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea | 2mg | $48 | 2026-05-28 | Buy |
| aablocks | AA00366H | 1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea | 5mg | $79 | 2026-05-28 | Buy |
| aablocks | AA00366H | 1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea | 10mg | $116 | 2026-05-28 | Buy |
| aablocks | AA00366H | 1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea ≥98% | 25mg | $219 | 2026-05-28 | Buy |
| aablocks | AA00366H | 1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea ≥98% | 50mg | $292 | 2026-05-28 | Buy |
| aablocks | AA00366H | 1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea | 100mg | $550 | 2026-05-28 | Buy |
| aablocks | AA00366H | 1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea | 200mg | $761 | 2026-05-28 | Buy |
| ACHEMBLOCK | X212070 | AT9283 97% | 100MG | $790 | 2026-05-27 | Buy |
| ACHEMBLOCK | X212070 | AT9283 97% | 20MG | $280 | 2026-05-27 | Buy |
| Adipogen Life Sciences | SYN-1011-M010 | AT9283 ≥95% | 10mg | $270 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1011-M050 | AT9283 ≥95% | 50mg | $799 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1011-M005 | AT9283 ≥95% | 5mg | $162 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1011-M001 | AT9283 ≥95% | 1mg | $86 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1011-M001 | AT9283 ≥95% | 1mg | $86 | 2026-05-06 | Buy |
| AK Scientific | X7478 | 1-cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea | 250mg | $1887 | 2021-12-16 | Buy |
| AK Scientific | X7478 | 1-cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea | 1g | $4132 | 2021-12-16 | Buy |
Properties
Density :1.45
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :insoluble in H2O; ≥19.05 mg/mL in DMSO; ≥47.6 mg/mL in EtOH with ultrasonic
form :solid
pka :10.58±0.10(Predicted)
color :White to off-white
InChIKey :LOLPPWBBNUVNQZ-UHFFFAOYSA-N
SMILES :[nH]1nc(c(c1)NC(=O)NC5CC5)c2[nH]c3c(n2)ccc(c3)CN4CCOCC4
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :insoluble in H2O; ≥19.05 mg/mL in DMSO; ≥47.6 mg/mL in EtOH with ultrasonic
form :solid
pka :10.58±0.10(Predicted)
color :White to off-white
InChIKey :LOLPPWBBNUVNQZ-UHFFFAOYSA-N
SMILES :[nH]1nc(c(c1)NC(=O)NC5CC5)c2[nH]c3c(n2)ccc(c3)CN4CCOCC4
Safety Information
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Description
AT-9283 is a broad spectrum kinase inhibitor that potently inhibits Aurora A, Aurora B, JAK2, JAK3, and c-ABL (IC50s = 3, 3, 1.2, 1.1, and 4 nM, respectively). It also potently (IC50 = <1 μM) inhibits many other kinases, including serine/threonine kinases as well as receptor and non-receptor tyrosine kinases. As Aurora kinases have roles in mitosis, inhibitors of these kinases, including AT-9283, have potential in cancer therapy. Consistent with this, AT-9283 is effective in preventing proliferation of cancer cells both in vitro and in vivo and this effect may be enhanced by combination therapy with other chemotherapeutics.Related product price
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