Tucatinib
|
- $90 - $2500
- Product name: Tucatinib
- CAS: 937263-43-9
- MF: C26H24N8O2
- MW: 480.52
- EINECS:200-001-8
- MDL Number:MFCD22380467
- Synonyms:ONT-380);N4-(4-([1;N6-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4,6-quinazolinediamine;Irbinitinib;Irbinitinib(ARRY380);(R)-N6-(4-Methyl-4;5-dihydrooxazol-2-yl)-N4-(3-Methyl-4-(thiazol-2-ylMethoxy)phenyl)quinazoline-4;6-diaMine
10 prices
Selected condition：
Brand
- AK Scientific
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 10mg
- 25mg
- 50mg
- 100mg
- 500mg
- 10g
- ManufacturerAK Scientific
- Product number8979DH
- Product descriptionTucatinib
- Packaging25mg
- Price$590
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM142733
- Product descriptionN4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine 98%
- Packaging100mg
- Price$982
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3906
- Product descriptionTucatinib 99.82%
- Packaging10mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3906
- Product descriptionTucatinib 99.82%
- Packaging50mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3906
- Product descriptionTucatinib 99.82%
- Packaging100mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3906
- Product descriptionTucatinib 99.82%
- Packaging500mg
- Price$1650
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000173
- Product descriptionIrbinitinib 98+%
- Packaging50mg
- Price$243
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000173
- Product descriptionIrbinitinib 98+%
- Packaging100mg
- Price$445
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8771
- Product descriptionTucatinib(Irbinitinib,ARRY-380) >98%
- Packaging10g
- Price$2500
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberD449790
- Product descriptionARRY-380
- Packaging25mg
- Price$1760
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8979DH | Tucatinib | 25mg | $590 | 2021-12-16 | Buy |
| Chemenu | CM142733 | N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine 98% | 100mg | $982 | 2021-12-16 | Buy |
| ChemScene | CS-3906 | Tucatinib 99.82% | 10mg | $90 | 2021-12-16 | Buy |
| ChemScene | CS-3906 | Tucatinib 99.82% | 50mg | $250 | 2021-12-16 | Buy |
| ChemScene | CS-3906 | Tucatinib 99.82% | 100mg | $450 | 2021-12-16 | Buy |
| ChemScene | CS-3906 | Tucatinib 99.82% | 500mg | $1650 | 2021-12-16 | Buy |
| Crysdot | CD31000173 | Irbinitinib 98+% | 50mg | $243 | 2021-12-16 | Buy |
| Crysdot | CD31000173 | Irbinitinib 98+% | 100mg | $445 | 2021-12-16 | Buy |
| DC Chemicals | DC8771 | Tucatinib(Irbinitinib,ARRY-380) >98% | 10g | $2500 | 2021-12-16 | Buy |
| TRC | D449790 | ARRY-380 | 25mg | $1760 | 2021-12-16 | Buy |
Properties
Density :1.41±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF:1.0(Max Conc. mg/mL);2.08(Max Conc. mM)
DMSO:49.0(Max Conc. mg/mL);101.97(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:2):0.33(Max Conc. mg/mL);0.69(Max Conc. mM) form :A crystalline solid
pka :6.61±0.70(Predicted)
InChIKey :SDEAXTCZPQIFQM-UHFFFAOYSA-N
SMILES :N1=C2C(C=C(NC3=NC(C)(C)CO3)C=C2)=C(NC2=CC=C(OC3C=CN4N=CN=C4C=3)C(C)=C2)N=C1
storage temp. :Store at -20°C
solubility :DMF:1.0(Max Conc. mg/mL);2.08(Max Conc. mM)
DMSO:49.0(Max Conc. mg/mL);101.97(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:2):0.33(Max Conc. mg/mL);0.69(Max Conc. mM) form :A crystalline solid
pka :6.61±0.70(Predicted)
InChIKey :SDEAXTCZPQIFQM-UHFFFAOYSA-N
SMILES :N1=C2C(C=C(NC3=NC(C)(C)CO3)C=C2)=C(NC2=CC=C(OC3C=CN4N=CN=C4C=3)C(C)=C2)N=C1
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Tucatinib is also known as ARRY-380 or Irbinitinib. ARRY-380 is an orally inhibitor of human epidermal growth factor receptor tyrosine kinase ErbB-2 (also called HER2) with potential antineoplastic activity. It selectively binds to and inhibits the phosphorylation of ErbB-2, which may prevent the activation of ErbB-2 signal transduction pathways, resulting in growth inhibition and death of ErbB-2-expressing tumor cells. ErbB-2 is overexpressed in a variety of cancers and plays an important role in cellular proliferation and differentiation. Therefore, ARRY-380 may be an alternative treatmentmethod for the treatment of HER2+ cancers.More related product prices
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