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ChemicalBook >> CAS DataBase List >> Ivosidenib

Ivosidenib

Ivosidenib price.
  • $16 - $1200
  • Product name: Ivosidenib
  • CAS: 1448347-49-6
  • MF: C28H22ClF3N6O3
  • MW: 582.96
  • EINECS:-0
  • MDL Number:MFCD29036964
  • Synonyms:RG120 100MG;(S)-N-((S)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide;(2S)-1-(4-Cyano-2-pyridinyl)-5-oxo-L-prolyl-2-(2-chlorophenyl)-N-(3,3-difluorocyclobutyl)-N2-(5-fluoro-3-pyridinyl)glycinamide;Glycinamide, 1-(4-cyano-2-pyridinyl)-5-oxo-L-prolyl-2-(2-chlorophenyl)-N-(3,3-difluorocyclobutyl)-N2-(5-fluoro-3-pyridinyl)-, (2S)-;AG120;AG 120;CS-1721;EOS-60845;Ivosidenib(AG-120)
Price62 Properties Safety Information Description
62 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
Package
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 100.00mg
  • 250.00mg
  • 10mM*1mLinDMSO
  • 250mg
  • 1.00g
  • 1g
  • Manufactureraablocks
  • Product numberAA00ABLB
  • Product description(2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide 98%
  • Packaging1mg
  • Price$16
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABLB
  • Product description(2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide 98%
  • Packaging5mg
  • Price$19
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABLB
  • Product description(2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide 98%
  • Packaging10mg
  • Price$23
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABLB
  • Product description(2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide 98%
  • Packaging25mg
  • Price$28
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABLB
  • Product description(2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide 98%
  • Packaging50mg
  • Price$39
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABLB
  • Product description(2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide 98%
  • Packaging100mg
  • Price$63
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABLB
  • Product description(2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide 98%
  • Packaging250mg
  • Price$106
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ABLB
  • Product description(2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide 95%
  • Packaging1g
  • Price$388
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS86637
  • Product descriptionIvosidenib 98%
  • Packaging1G
  • Price$550
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS86637
  • Product descriptionIvosidenib 98%
  • Packaging1G
  • Price$550
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS86637
  • Product descriptionIvosidenib 98%
  • Packaging25MG
  • Price$30
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS86637
  • Product descriptionIvosidenib 98%
  • Packaging25MG
  • Price$30
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS86637
  • Product descriptionIvosidenib 98%
  • Packaging100MG
  • Price$80
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS86637
  • Product descriptionIvosidenib 98%
  • Packaging100MG
  • Price$80
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number0862DV
  • Product descriptionIvosidenib
  • Packaging25mg
  • Price$387
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004922
  • Product descriptionIVOSIDENIB 95.00%
  • Packaging5MG
  • Price$502.8
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00ABLB (2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide 98% 1mg $16 2026-05-28 Buy
aablocks AA00ABLB (2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide 98% 5mg $19 2026-05-28 Buy
aablocks AA00ABLB (2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide 98% 10mg $23 2026-05-28 Buy
aablocks AA00ABLB (2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide 98% 25mg $28 2026-05-28 Buy
aablocks AA00ABLB (2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide 98% 50mg $39 2026-05-28 Buy
aablocks AA00ABLB (2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide 98% 100mg $63 2026-05-28 Buy
aablocks AA00ABLB (2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide 98% 250mg $106 2026-05-28 Buy
aablocks AA00ABLB (2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide 95% 1g $388 2026-05-28 Buy
ACHEMBLOCK S86637 Ivosidenib 98% 1G $550 2026-05-25 Buy
ACHEMBLOCK S86637 Ivosidenib 98% 1G $550 2026-05-27 Buy
ACHEMBLOCK S86637 Ivosidenib 98% 25MG $30 2026-05-25 Buy
ACHEMBLOCK S86637 Ivosidenib 98% 25MG $30 2026-05-27 Buy
ACHEMBLOCK S86637 Ivosidenib 98% 100MG $80 2026-05-25 Buy
ACHEMBLOCK S86637 Ivosidenib 98% 100MG $80 2026-05-27 Buy
AK Scientific 0862DV Ivosidenib 25mg $387 2021-12-16 Buy
American Custom Chemicals Corporation INB0004922 IVOSIDENIB 95.00% 5MG $502.8 2021-12-16 Buy
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Properties

Melting point :151-173°C
Boiling point :854.3±65.0 °C(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :11.58±0.40(Predicted)
form :Solid
color :White to Off-White
InChIKey :KZEDTWHGUDPGAF-UPVQGACJSA-N
SMILES :C(N(C1N(O)CC=C(C#N)C=1)C(=O)[C@@H]1CCON1)(=O)[C@H](C1=CC=CC=C1Cl)N(C1CC(F)(F)C1)C1=CC(F)=CN=C1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) that specifically inhibits a mutated form of IDH1 in the cytoplasm, preventing the formation of 2-hydroxyglutarate. AG-120 may induce cellular differentiation as well as inhibit proliferation in IDH1-expressing tumor cells.

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