Lonidamine
|
- $10 - $1504.5
- Product name: Lonidamine
- CAS: 50264-69-2
- MF: C15H10Cl2N2O2
- MW: 321.16
- EINECS:256-510-0
- MDL Number:MFCD00866285
- Synonyms:af1890 ;1-[(2,4-dichlorophenyl)methyl]indazole-3-carboxylic acid;1H-Indazole-3-carboxylicacid, 1-[(2,4-dichlorophenyl)Methyl]-;1-(2,4-dichlorbenzyl)-indazole-3-carboxylicacid ;1-(2,4-dichlorobenzyl)-1h-indazole-3-carboxylicaci ;Lonidamine, >=99%;1-(3,4-dichlorobenzyl)-1H-indazole-3-carboxylic acid;DICLONDAZOLIC ACID
49 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Tocris
- Usbiological
Package
- 25mg
- 10mM*1mLinDMSO
- 5mg
- 10mg
- 50
- 10
- 50mg
- EvaluationSample
- 10mM(in1mLDMSO)
- 100mg
- 250mg
- 500mg
- 1g
- 5g
- ManufacturerAK Scientific
- Product numberC483
- Product descriptionLonidamine
- Packaging25mg
- Price$94
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1964
- Product descriptionLonidamine
- Packaging10mM(in1mLDMSO)
- Price$61
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1964
- Product descriptionLonidamine
- PackagingEvaluationSample
- Price$30
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1964
- Product descriptionLonidamine
- Packaging5mg
- Price$51
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberAS526212
- Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
- Packaging100mg
- Price$48
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS526212
- Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
- Packaging5mg
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS526212
- Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
- Packaging10mg
- Price$13
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS526212
- Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
- Packaging50mg
- Price$26
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS526212
- Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
- Packaging250mg
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS526212
- Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
- Packaging1g
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS526212
- Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
- Packaging5g
- Price$631
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number6499
- Product descriptionLonidamine 98%
- Packaging50mg
- Price$175
- Updated2026-05-22
- Buy
- ManufacturerAxon Medchem
- Product numberAxon4333
- Product descriptionLonidamine
- Packaging50mg
- Price$176
- Updated2026-05-19
- Buy
- ManufacturerAxon Medchem
- Product numberAxon4333
- Product descriptionLonidamine
- Packaging10mg
- Price$88
- Updated2026-05-19
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134504
- Product descriptionLonidamine >99%
- Packaging100mg
- Price$510
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134504
- Product descriptionLonidamine >99%
- Packaging250mg
- Price$765
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | C483 | Lonidamine | 25mg | $94 | 2021-12-16 | Buy |
| ApexBio Technology | B1964 | Lonidamine | 10mM(in1mLDMSO) | $61 | 2026-05-06 | Buy |
| ApexBio Technology | B1964 | Lonidamine | EvaluationSample | $30 | 2026-05-06 | Buy |
| ApexBio Technology | B1964 | Lonidamine | 5mg | $51 | 2026-05-06 | Buy |
| Arctom | AS526212 | 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% | 100mg | $48 | 2021-12-16 | Buy |
| Arctom | AS526212 | 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% | 5mg | $10 | 2021-12-16 | Buy |
| Arctom | AS526212 | 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% | 10mg | $13 | 2021-12-16 | Buy |
| Arctom | AS526212 | 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% | 50mg | $26 | 2021-12-16 | Buy |
| Arctom | AS526212 | 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% | 250mg | $72 | 2021-12-16 | Buy |
| Arctom | AS526212 | 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% | 1g | $175 | 2021-12-16 | Buy |
| Arctom | AS526212 | 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% | 5g | $631 | 2021-12-16 | Buy |
| AvaChem | 6499 | Lonidamine 98% | 50mg | $175 | 2026-05-22 | Buy |
| Axon Medchem | Axon4333 | Lonidamine | 50mg | $176 | 2026-05-19 | Buy |
| Axon Medchem | Axon4333 | Lonidamine | 10mg | $88 | 2026-05-19 | Buy |
| Biorbyt Ltd | orb134504 | Lonidamine >99% | 100mg | $510 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134504 | Lonidamine >99% | 250mg | $765 | 2021-12-16 | Buy |
Properties
Melting point :207-209°C
Boiling point :537.9±45.0 °C(Predicted)
Density :1.4835 (rough estimate)
refractive index :1.6070 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml).
form :solid
pka :3.00±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChI :InChI=1S/C15H10Cl2N2O2/c16-10-6-5-9(12(17)7-10)8-19-13-4-2-1-3-11(13)14(18-19)15(20)21/h1-7H,8H2,(H,20,21)
InChIKey :WDRYRZXSPDWGEB-UHFFFAOYSA-N
SMILES :N1(CC2=CC=C(Cl)C=C2Cl)C2=C(C=CC=C2)C(C(O)=O)=N1
CAS DataBase Reference :50264-69-2(CAS DataBase Reference)
Boiling point :537.9±45.0 °C(Predicted)
Density :1.4835 (rough estimate)
refractive index :1.6070 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml).
form :solid
pka :3.00±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChI :InChI=1S/C15H10Cl2N2O2/c16-10-6-5-9(12(17)7-10)8-19-13-4-2-1-3-11(13)14(18-19)15(20)21/h1-7H,8H2,(H,20,21)
InChIKey :WDRYRZXSPDWGEB-UHFFFAOYSA-N
SMILES :N1(CC2=CC=C(Cl)C=C2Cl)C2=C(C=CC=C2)C(C(O)=O)=N1
CAS DataBase Reference :50264-69-2(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | ||||||||||||||||||||||||||||
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Description
Lonidamine is a derivative of indazole-3-carboxylic acid. It is a kind of orally administrated small molecule, which can inhibit the glycolysis process through inactivating the hexokinase (the first step in glycolysis). It has been shown that cancer cell primarily generates energy through glycolysis process. Therefore, Lonidamine has been used for the treatment of several kinds of cancers. One special property of Lonidamine is that it seems to enhance aerobic glycolysis in normal cells, but inhibit glycolysis only in cancer cells. In addition, there are also evidences that Lonidamine may increase the occurrence of apoptosis. It has also been shown that Lonidamine is effective in the treatment of benigh prostatic hyperplasia (BPH).Related product price
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