Tranilast
|
- $5 - $1732.5
- Product name: Tranilast
- CAS: 53902-12-8
- MF: C18H17NO5
- MW: 327.33
- EINECS:
- MDL Number:MFCD00864787
- Synonyms:2-((3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)amino)-benzoicaci ;n-(3,4-dimethoxycinnamoyl)-anthranilicaci ;n-5’ ;rizaben ;SB-252218;N-(3',4'-DIMETHOXYCINNAMOYL)ANTHRANILIC ACID;2-[[3-(3,4-DIMETHOXYPHENYL)-1-OXO-2-PROPENYL]AMINO] BENZOIC ACID;TRANILAST
93 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Atlantic Research Chemicals
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemcia Scientific
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 10mg
- 10mM*1mLinDMSO(Solution)
- 50g
- 250g
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM*1mLinDMSO
- 50
- 1.00g
- 5.00g
- 1 unit
- 10 mg
- 10mM(in1mLDMSO)
- 5mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500MG
- 1g
- 5g
- 10g
- 25g
- 100g
- Manufactureraablocks
- Product numberAA003URN
- Product description2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]benzoic acid ≥98%(HPLC)
- Packaging250mg
- Price$11
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003URN
- Product description2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]benzoic acid ≥98%(HPLC)
- Packaging1g
- Price$16
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003URN
- Product description2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]benzoic acid 99%
- Packaging5g
- Price$38
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003URN
- Product description2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]benzoic acid ≥98%(HPLC)
- Packaging25g
- Price$175
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003URN
- Product description2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]benzoic acid ≥98%(HPLC)
- Packaging100g
- Price$578
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX191388
- Product description2-[3-(3,4-Dimethoxyphenyl)acrylamido]benzoic acid 95.00%
- Packaging25G
- Price$110
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberI586
- Product descriptionTranilast 98%(HPLC)
- Packaging1g
- Price$118
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ10509
- Product descriptionTranilast >98%(HPLC),powder
- Packaging25mg
- Price$82
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ98401
- Product descriptionTranilast 95%
- Packaging1g
- Price$89
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ10509
- Product descriptionTranilast >98%(HPLC),powder
- Packaging5mg
- Price$42
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ10509
- Product descriptionTranilast >98%(HPLC),powder
- Packaging100mg
- Price$161
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ98401
- Product descriptionTranilast
- Packaging5g
- Price$260
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ98401
- Product descriptionTranilast 95%
- Packaging5g
- Price$268
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberI586
- Product descriptionTranilast 98%(HPLC)
- Packaging5g
- Price$358
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ98401
- Product descriptionTranilast
- Packaging10g
- Price$480
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ98401
- Product descriptionTranilast 95%
- Packaging10g
- Price$495
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA003URN | 2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]benzoic acid ≥98%(HPLC) | 250mg | $11 | 2026-05-28 | Buy |
| aablocks | AA003URN | 2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]benzoic acid ≥98%(HPLC) | 1g | $16 | 2026-05-28 | Buy |
| aablocks | AA003URN | 2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]benzoic acid 99% | 5g | $38 | 2026-05-28 | Buy |
| aablocks | AA003URN | 2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]benzoic acid ≥98%(HPLC) | 25g | $175 | 2026-05-28 | Buy |
| aablocks | AA003URN | 2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]benzoic acid ≥98%(HPLC) | 100g | $578 | 2026-05-28 | Buy |
| ACHEMBLOCK | X191388 | 2-[3-(3,4-Dimethoxyphenyl)acrylamido]benzoic acid 95.00% | 25G | $110 | 2026-05-27 | Buy |
| AK Scientific | I586 | Tranilast 98%(HPLC) | 1g | $118 | 2026-06-04 | Buy |
| AK Scientific | J10509 | Tranilast >98%(HPLC),powder | 25mg | $82 | 2026-06-04 | Buy |
| AK Scientific | J98401 | Tranilast 95% | 1g | $89 | 2026-06-04 | Buy |
| AK Scientific | J10509 | Tranilast >98%(HPLC),powder | 5mg | $42 | 2026-06-04 | Buy |
| AK Scientific | J10509 | Tranilast >98%(HPLC),powder | 100mg | $161 | 2026-06-04 | Buy |
| AK Scientific | J98401 | Tranilast | 5g | $260 | 2021-12-16 | Buy |
| AK Scientific | J98401 | Tranilast 95% | 5g | $268 | 2026-06-04 | Buy |
| AK Scientific | I586 | Tranilast 98%(HPLC) | 5g | $358 | 2026-06-04 | Buy |
| AK Scientific | J98401 | Tranilast | 10g | $480 | 2021-12-16 | Buy |
| AK Scientific | J98401 | Tranilast 95% | 10g | $495 | 2026-06-04 | Buy |
Properties
Melting point :166.2-168.2 °C (lit.)
Boiling point :465.23°C (rough estimate)
Density :1.3185 (rough estimate)
refractive index :1.5100 (estimate)
storage temp. :2-8°C
solubility :DMSO: 18 mg/mL
form :powder
pka :3.47±0.36(Predicted)
color :white to beige
Merck :14,9570
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI :1S/C18H17NO5/c1-23-15-9-7-12(11-16(15)24-2)8-10-17(20)19-14-6-4-3-5-13(14)18(21)22/h3-11H,1-2H3,(H,19,20)(H,21,22)/b10-8+
InChIKey :NZHGWWWHIYHZNX-CSKARUKUSA-N
SMILES :COc1ccc(\C=C\C(=O)Nc2ccccc2C(O)=O)cc1OC
CAS DataBase Reference :53902-12-8(CAS DataBase Reference)
Boiling point :465.23°C (rough estimate)
Density :1.3185 (rough estimate)
refractive index :1.5100 (estimate)
storage temp. :2-8°C
solubility :DMSO: 18 mg/mL
form :powder
pka :3.47±0.36(Predicted)
color :white to beige
Merck :14,9570
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI :1S/C18H17NO5/c1-23-15-9-7-12(11-16(15)24-2)8-10-17(20)19-14-6-4-3-5-13(14)18(21)22/h3-11H,1-2H3,(H,19,20)(H,21,22)/b10-8+
InChIKey :NZHGWWWHIYHZNX-CSKARUKUSA-N
SMILES :COc1ccc(\C=C\C(=O)Nc2ccccc2C(O)=O)cc1OC
CAS DataBase Reference :53902-12-8(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
Tranilast is a compound that exhibits anti-inflammatory and immunomodulatory effects by inhibiting lipid mediator and cytokine release from inflammatory cells and interfering with PDGF- and TGF-β1-induced proliferation and migration of vascular medial smooth muscle cells. Tranilast suppresses production of prostaglandin D2 (IC50 = 0.1 mM), prostaglandin E2 (IC50 = ~1-20 μM), thromboxane B2 (IC50 = ~10-50 μM), TGF-β1 (IC50 = ~100-200 μM), and interleukin-8 (IC50 = ~100 μM) in in vitro models as well as attenuates of the proinflammatory activity of human monocytes. While originally marketed as an antiallergenic drug, the efficacy of tranilast in preventing restenosis after percutaneous coronary intervention has been tested in a large-scale clinical trial. Additionally, tranilast inhibits VEGF-induced angiogenetic activities (i.e., proliferation, migration and tube formation of vascular endothelial cells) with IC50 values of 22, 18 and 193 μM, which may prove therapeutic for various retinal diseases.Related product price
-
3,4-Diaminobenzoic acid
$6-2433.7 -
ANTHRANILIC ACID CINNAMYL ESTER
$56.65-168.65 -
4-Aminobenzoic acid
$4-1325
