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ChemicalBook >> CAS DataBase List >> Z-Vad-fmk, non-methylated

Z-Vad-fmk, non-methylated

Z-Vad-fmk, non-methylated price.
  • $73 - $3200
  • Product name: Z-Vad-fmk, non-methylated
  • CAS: 161401-82-7
  • MF: C21H28FN3O7
  • MW: 453.46
  • EINECS:
  • MDL Number:
  • Synonyms:Z-VAL-ALA-ASP-(OH)-FLUOROMETHYL KETONE;Z-VAD-FMK (Caspase Inhibitor VI);Carbobenzyloxy-Val-Ala-Asp-alpha-fluoromethylketone;L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]-;L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]- (9ci);L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(carboxymethyl)-3-fluoro-2-oxopropyl]-, (S)-;Z-VAD-FMK, Free Acid;Z-VAD(OH)-FMK (Caspase Inhibitor VI)
12 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • Cayman Chemical
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 250μg
  • 500μg
  • 1mg
  • 5mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number1838CP
  • Product descriptionBenzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone
  • Packaging5mg
  • Price$521
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA834991
  • Product description(5S,8S,11S)-11-(2-Fluoroacetyl)-5-isopropyl-8-methyl-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatridecan-13-oicacid 98+%
  • Packaging1mg
  • Price$91
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA834991
  • Product description(5S,8S,11S)-11-(2-Fluoroacetyl)-5-isopropyl-8-methyl-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatridecan-13-oicacid 98+%
  • Packaging5mg
  • Price$267
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA834991
  • Product description(5S,8S,11S)-11-(2-Fluoroacetyl)-5-isopropyl-8-methyl-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatridecan-13-oicacid 98+%
  • Packaging50mg
  • Price$1903
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA834991
  • Product description(5S,8S,11S)-11-(2-Fluoroacetyl)-5-isopropyl-8-methyl-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatridecan-13-oicacid 98+%
  • Packaging100mg
  • Price$2633
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14467
  • Product descriptionZ-VAD(OH)-FMK ≥95%
  • Packaging500μg
  • Price$73
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14467
  • Product descriptionZ-VAD(OH)-FMK ≥95%
  • Packaging1mg
  • Price$131
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14467
  • Product descriptionZ-VAD(OH)-FMK ≥95%
  • Packaging5mg
  • Price$380
  • Updated2024-03-01
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN19230
  • Product descriptionZ-VAD-FMK
  • Packaging1mg
  • Price$101
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8639
  • Product descriptionZ-VAD(OH)-FMK >99%
  • Packaging250mg
  • Price$3200
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number219007
  • Product descriptionCaspase Inhibitor VI - CAS 161401-82-7 - Calbiochem
    Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies.
  • Packaging1mg
  • Price$303
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number219007
  • Product descriptionCaspase Inhibitor VI - CAS 161401-82-7 - Calbiochem Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies.
  • Packaging250μg
  • Price$113
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1838CP Benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone 5mg $521 2021-12-16 Buy
Ambeed A834991 (5S,8S,11S)-11-(2-Fluoroacetyl)-5-isopropyl-8-methyl-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatridecan-13-oicacid 98+% 1mg $91 2021-12-16 Buy
Ambeed A834991 (5S,8S,11S)-11-(2-Fluoroacetyl)-5-isopropyl-8-methyl-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatridecan-13-oicacid 98+% 5mg $267 2021-12-16 Buy
Ambeed A834991 (5S,8S,11S)-11-(2-Fluoroacetyl)-5-isopropyl-8-methyl-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatridecan-13-oicacid 98+% 50mg $1903 2021-12-16 Buy
Ambeed A834991 (5S,8S,11S)-11-(2-Fluoroacetyl)-5-isopropyl-8-methyl-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatridecan-13-oicacid 98+% 100mg $2633 2021-12-16 Buy
Cayman Chemical 14467 Z-VAD(OH)-FMK ≥95% 500μg $73 2024-03-01 Buy
Cayman Chemical 14467 Z-VAD(OH)-FMK ≥95% 1mg $131 2024-03-01 Buy
Cayman Chemical 14467 Z-VAD(OH)-FMK ≥95% 5mg $380 2024-03-01 Buy
CSNpharm CSN19230 Z-VAD-FMK 1mg $101 2021-12-16 Buy
DC Chemicals DC8639 Z-VAD(OH)-FMK >99% 250mg $3200 2021-12-16 Buy
Sigma-Aldrich 219007 Caspase Inhibitor VI - CAS 161401-82-7 - Calbiochem
Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies.
1mg $303 2024-03-01 Buy
Sigma-Aldrich 219007 Caspase Inhibitor VI - CAS 161401-82-7 - Calbiochem Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies. 250μg $113 2024-03-01 Buy

Properties

Boiling point :758.0±60.0 °C(Predicted)
Density :1.260±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO:5.0(Max Conc. mg/mL);11.0(Max Conc. mM)
pka :3.91±0.19(Predicted)
form :Off-white solid

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Z-VAD(OH)-FMK is an irreversible tripeptide inhibitor of all caspases. This non-methylated form is useful in studies involving recombinant, isolated, or purified enzymes. Unlike the methylated form, Z-VAD(OMe)-FMK , this compound does not require pretreatment with esterases prior to in vitro use.

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