ChemicalBook CAS DataBase List 1,1,1,3,3,3-Hexafluoro-2-propanol

1,1,1,3,3,3-Hexafluoro-2-propanol synthesis

14synthesis methods

Product Name:1,1,1,3,3,3-Hexafluoro-2-propanol
CAS Number:920-66-1
Molecular formula:C3H2F6O
Molecular Weight:168.04

Chloromethyl-1,1,1,3,3,3-hexafluoroisopropyl ether

26103-07-1
47 suppliers
$10.00/1g

920-66-1
590 suppliers
$6.00/10g

28523-86-6
197 suppliers
$25.00/5G

Yield:28523-86-6 93% ，920-66-1 1.05 %Chromat.

Reaction Conditions:

with hydrogenchloride;potassium fluoride;water;Aliquat HTA-1 at 100; for 3 h;Product distribution / selectivity;

Steps:

13

EXAMPLE 13; A mixture of (CF₃)₂CHOCH₂C143.2 g (0.2 mole), potassium fluoride 12.76 g (0.22 mole), 10 cc of 1.0 N HCl (0.01 mole), and 1 g of Aliquat HTA-I was heated at 100 °C for S hours. Water was added to dissolve the precipitated salts, and the product was recovered by azeotropic distillation using a Dean Stark trap. The recovered product weighed 38.7 g and was analyzed by gas chromatography. The product was 80% (CF₃)₂CHOCH₂F and 18.5% (CF₃)₂CHOCH₂C1. There was 1.05% of (CF₃)₂CHOH. Conversion was 83% and yield was 93%.