ChemicalBook CAS DataBase List 1,2-Bis(2-chloroethoxy)ethane

1,2-Bis(2-chloroethoxy)ethane synthesis

11synthesis methods

Product Name:1,2-Bis(2-chloroethoxy)ethane
CAS Number:112-26-5
Molecular formula:C6H12Cl2O2
Molecular Weight:187.06

112-27-6 Synthesis

112-27-6
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112-26-5
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Yield:112-26-5 91%

Reaction Conditions:

with pyridine;thionyl chloride in 1,4-dioxane at 80;

Steps:

Preparation of dichloroethylene glycol,Specifically, the following steps are included
General procedure: S1, 1mol of diol and 3mol of pyridine are dissolved into 500mL of dioxane, and heated, heated to 80 ° C;S2, adding 2.2 mol of thionyl chloride to the product in step S1, slowly dropping, adding 2-3 h, and after the completion of the dropwise addition, reacting at 80 ° C for 5-6 h;S3, the product solution in step S2 is naturally cooled to room temperature, and dioxane is distilled off;S4, the residue in step S3 is added to ethyl acetate, stirred for 30 min, and the pyridinium salt is filtered off;S5. The filtrate in the step S4 was washed with water, and the ethyl acetate layer was dried over anhydrous sodium sulfate and evaporated.

References:

Shenghezhong New Kind Materials Science And Technology (Shanghai) Co., Ltd.;Yang Shaolong;Wang Hui;Wang Ziyue CN109824695, 2019, A Location in patent:Paragraph 0072; 0073; 0074-0079

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17134-17-7 Synthesis