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1-(6-Methyl-2-pyridyl)acetone synthesis

2synthesis methods
-

Yield:65702-08-1 90%

Reaction Conditions:

Stage #1: 2,6-dimethylpyridinewith n-butyllithium in tetrahydrofuran at -78; for 1 h;Schlenk technique;Inert atmosphere;
Stage #2: N,N-dimethyl acetamide in tetrahydrofuran at -78; for 0.5 h;

References:

Broese, Timo;Ehlers, Peter;Langer, Peter;von Langermann, Jan [ChemBioChem,2021,vol. 22,# 23,p. 3314 - 3318]

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