1-BOC-3-(4-CHLOROPHENYL)-3-HYDROXYPIPERIDINE synthesis
- Product Name:1-BOC-3-(4-CHLOROPHENYL)-3-HYDROXYPIPERIDINE
- CAS Number:951624-09-2
- Molecular formula:C16H22ClNO3
- Molecular Weight:311.8
106-39-8
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$14.00/5g
98977-36-7
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$6.00/1g
951624-09-2
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$65.50/25mg
Yield:-
Reaction Conditions:
Stage #1: bromochlorobenzenewith magnesium in tetrahydrofuran;
Stage #2: 3-oxo-piperidine-1-carboxylic acid tert-butyl ester in tetrahydrofuran;
References:
Kumagai, Toshihito;Okubo, Taketoshi;Kataoka-Okubo, Hiromi;Chaki, Shigeyuki;Okuyama, Shigeru;Nakazato, Atsuro [Bioorganic and Medicinal Chemistry,2001,vol. 9,# 5,p. 1349 - 1355]