Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 1-Methylpiperidin-4-amine

1-Methylpiperidin-4-amine synthesis

8synthesis methods
-

Yield:41838-46-4 100%

Reaction Conditions:

with ammonium formate;palladium on carbon in methanol;

Steps:

25.3A.1

Step: 3A-1Synthesis of l-Methyl-piperidin-4-yIamineProcedure:Ammonium formate (2.226g, 0.035348mol) was added to a solution of 1 -Methyl- piperidin-4-one (lg, 0.008837mol) in MeOH and stirred for lOmins. 20% Pd-C was added to this and the reaction mixture was heated at 60°C for 2hrs. The reaction was monitored by the TLC (10% methanol in chloroform). The reaction mixture was filtered through celite bed, concentrated to afford lg (100% yield) of l-Methyl-piperidin-4-ylamine.

References:

WO2012/59932,2012,A1 Location in patent:Page/Page column 137

1-Methylpiperidin-4-amine Related Search: