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(S)-2-[5-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1H-imidazol-2-y synthesis

9synthesis methods
1007882-04-3 Synthesis
(S)-tert-butyl 2-(5-(4-bromophenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate

1007882-04-3
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(S)-2-[5-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1H-imidazol-2-y

1007882-12-3
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Yield:1007882-12-3 92%

Reaction Conditions:

with bis-triphenylphosphine-palladium(II) chloride;potassium acetate in Dimethyl ether at 90; for 5 h;Inert atmosphere;Large scale;

References:

An, Delie;Dong, Wanrong;Fang, Qinghong;Feng, Yahui;Huang, Enhuo;Liu, Haiwang;Peng, Zhihong;Xiang, Xuwen;Xie, Hongming;Zhang, Yingjun [Organic Process Research and Development,2021,vol. 25,# 4,p. 838 - 848]