6-Amino-2-aza-spiro[3.3]heptane-2-carboxylic acid tert-butyl ester synthesis
- Product Name:6-Amino-2-aza-spiro[3.3]heptane-2-carboxylic acid tert-butyl ester
- CAS Number:1211586-09-2
- Molecular formula:C11H20N2O2
- Molecular Weight:212.29
![tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate](/CAS2/GIF/1181816-12-5.gif)
1181816-12-5
189 suppliers
$9.00/100mg
1211586-09-2
133 suppliers
$46.00/100mg
Yield:-
Steps:
Multi-step reaction with 3 steps
1: methanol; sodium tetrahydroborate / 1 h / 0 - 25 °C / Inert atmosphere
2: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 16 h / 0 - 25 °C / Inert atmosphere
3: hydrazine hydrate / ethanol / 1.5 h / 25 °C
References:
Xuanzhu Pharma Co., Ltd.;WU, Frank EP3281942, 2018, A1
![tert-butyl 6-azido-2-azaspiro[3.3]heptane-2-carboxylate](/CAS/20180527/GIF/1239320-12-7.gif)
1239320-12-7
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1211586-09-2
133 suppliers
$46.00/100mg
![2-Azaspiro[3.3]heptane-2-carboxylic acid 6-[[(phenylmethoxy)carbonyl]amino]-,1,1-dimethylethyl ester](/CAS/20180702/GIF/1239589-54-8.gif)
1239589-54-8
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1211586-09-2
133 suppliers
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![tert-butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate](/CAS2/GIF/1147557-97-8.gif)
1147557-97-8
131 suppliers
$14.00/100mg
1211586-09-2
133 suppliers
$46.00/100mg
![tert-butyl 6-((methylsulfonyl)oxy)-2-azaspiro[3.3]heptane-2-carboxylate](/CAS/20200401/GIF/1239320-11-6.gif)
1239320-11-6
16 suppliers
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1211586-09-2
133 suppliers
$46.00/100mg