Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
logo
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook

Welcome back!

Structured search
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
1396753-41-5

1H-Benzotriazole, 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- synthesis

5synthesis methods
944718-31-4 Synthesis
5-BroMo-1-Methyl-1H-benzo[d][1,2,3]triazole

944718-31-4
61 suppliers
$45.00/10mg

Bis(pinacolato)diboron

73183-34-3
593 suppliers
$6.00/5g

1H-Benzotriazole, 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

1396753-41-5
34 suppliers
inquiry

-

Yield:1396753-41-5 74%

Reaction Conditions:

with anhydrous potassium acetate;palladium (II) [1,1'-bis(diphenylphosphanyl)ferrocene] dichloride in 1,4-dioxane at 90; for 12 h;Inert atmosphere;

Steps:

95.4

Methyl-5-(4,4,5,5-tetramethyl-l,3,2-dioxaborolan-2-yl)-7H-benzo[i/][l,2,3]triazoleTo a solution of 5-bromo-l-methyl-iH-benzo[2 (86 mg, 0.12 mmol), AcOK (0.575 g, 5.86 mmol), and 4,4,4',4',5,5,5',5'-octamethyl-2,2'-bi(l,3,2-dioxaborolane) (658 mg, 2.59 mmol) under an N2 atmosphere. The resulting solution was stirred for 12 h at 90°C and then concentrated under vacuum to give a residue, which was purified via silica gel chromatography (2% ethyl acetate in petroleum ether) to afford l-methyl-5-(4,4,5,5-tetramethyl-l,3,2-dioxaborolan-2- yl)-7H-benzo[i/][l,2,3]triazole as a white solid (0.56 g, 74%).LC/MS (ES, m/z): [M+H]+.260.1*H-NMR (300 MHz, CDCI3) δ 8.57 (s, 1H), 7.90 - 7.93 (m, 1H), 7.50 - 7.55 (m, 1H), 4.33 (s, 3H), 1.36 (s, 12H)

References:

WO2012/119046,2012,A2 Location in patent:Page/Page column 208

364-73-8 Synthesis
4-Bromo-1-fluoro-2-nitrobenzene

364-73-8
273 suppliers
$8.00/10g

1H-Benzotriazole, 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

1396753-41-5
34 suppliers
inquiry

References
53484-26-7 Synthesis
4-bromo-N-methyl-2-nitroaniline

53484-26-7
84 suppliers
$30.00/250mg

1H-Benzotriazole, 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

1396753-41-5
34 suppliers
inquiry

References
69038-76-2 Synthesis
4-broMo-N1-Methylbenzene-1,2-diaMine

69038-76-2
75 suppliers
$28.00/100mg

1H-Benzotriazole, 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

1396753-41-5
34 suppliers
inquiry

References
32046-62-1 Synthesis
5-BROMO-1H-BENZOTRIAZOLE

32046-62-1
111 suppliers
$9.00/250mg

1H-Benzotriazole, 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

1396753-41-5
34 suppliers
inquiry

References