2-(4-broMophenyl)propanenitrile synthesis
- Product Name:2-(4-broMophenyl)propanenitrile
- CAS Number:42186-06-1
- Molecular formula:C9H8BrN
- Molecular Weight:210.07
Yield:42186-06-1 91%
Reaction Conditions:
Stage #1: 4-Bromophenylacetonitrile in tetrahydrofuran at -78; for 0.5 h;Inert atmosphere;
Stage #2: methyl iodide in tetrahydrofuran; for 1 h;Inert atmosphere;
References:
Turnbull, Ben W. H.;Evans, P. Andrew [Journal of the American Chemical Society,2015,vol. 137,# 19,p. 6156 - 6159] Location in patent:supporting information
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