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ChemicalBook CAS DataBase List 2,6-Di-tert-butyl-4-methylpyridine
38222-83-2

2,6-Di-tert-butyl-4-methylpyridine synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine / tetrahydrofuran / 18 h / 80 °C / Glovebox; Inert atmosphere
2: potassium tert-butylate; C21H30ClNPPd / tert-Amyl alcohol / 18 h / 65 °C / Glovebox; Inert atmosphere; Sealed tube

References:

Haydl, Alexander M.;Hartwig, John F. [Organic Letters,2019,vol. 21,# 5,p. 1337 - 1341]

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