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ChemicalBook CAS DataBase List 2,6-Dichloro-Benzotrifluoride

2,6-Dichloro-Benzotrifluoride synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: butyllithium / tetrahydrofuran; hexane / 2 h / -75 °C
1.2: 98 percent / iodine / tetrahydrofuran; hexane
2.1: 69 percent / potassium fluoride; cuprous iodide / 1-methyl-pyrrolidin-2-one / 6 h / 50 °C

References:

Schlosser, Manfred;Heiss, Christophe;Marzi, Elena;Scopelliti, Rosario [European Journal of Organic Chemistry,2006,# 19,p. 4398 - 4404]

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