2-[(Acetylthio)methyl]-phenylpropionic acid synthesis
- Product Name:2-[(Acetylthio)methyl]-phenylpropionic acid
- CAS Number:91702-98-6
- Molecular formula:C12H14O3S
- Molecular Weight:238.3
5669-19-2
507-09-5
91702-98-6
General procedure for the synthesis of 3-(acetylthio)-2-benzylpropionic acid from 2-benzylpropenoic acid and thioacetic acid: 16.2 g of 2-benzylpropenoic acid and 12.3 mL of thioacetic acid were added to a clean and dry round-bottomed flask, and the reaction was stirred for 1 hour at 30 °C. Subsequently, the reaction mixture was warmed up to 60 °C and the stirring reaction was continued for 4 hours. Upon completion of the reaction, the excess thioacetic acid was removed by distillation to give the crude product of 3-(acetylthio)-2-benzylpropionic acid. Yield: 23.8 g.
5669-19-2
312 suppliers
$15.00/5g
507-09-5
331 suppliers
$12.00/5g
91702-98-6
125 suppliers
$15.00/1g
Yield:91702-98-6 99%
Reaction Conditions:
in dichloromethane; for 1152 h;
References:
Neustadt;Smith;Nechuta;Bronnenkant;Haslanger;Watkins;Foster;Sybertz [Journal of Medicinal Chemistry,1994,vol. 37,# 15,p. 2461 - 2476]
507-09-5
331 suppliers
$12.00/5g
5669-19-2
312 suppliers
$15.00/5g
91702-98-6
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$15.00/1g
5669-19-2
312 suppliers
$15.00/5g
91702-98-6
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$15.00/1g
607-81-8
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$9.00/1g
91702-98-6
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616-75-1
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91702-98-6
125 suppliers
$15.00/1g