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ChemicalBook CAS DataBase List 2-AMINO-3-CHLOROBENZOTRIFLUORIDE

2-AMINO-3-CHLOROBENZOTRIFLUORIDE synthesis

8synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: 64 percent / 190 - 220 °C
2: 88 percent / Cl2 / 10 h / 220 °C / Irradiation
3: HF / 150 °C
4: 76 percent / H2NNH2 / H2O / 2 h / Heating

References:

Pavia;Lobbestael;Taylor;Hershenson;Miskell [Journal of Medicinal Chemistry,1990,vol. 33,# 2,p. 854 - 861]

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