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2-Butenoic acid, 4,4-diethoxy-, ethyl ester, (2E)- synthesis

11synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 65 percent / ZnCl2 / 3 h / 90 °C
2: K2CO3 / H2O

References:

Stambouli, A.;Chastrette, F.;Amouroux, R.;Chastrette, M.;Mattioda, G.;Blanc, A. [Tetrahedron Letters,1986,vol. 27,# 35,p. 4149 - 4152]