2-CYANO-N-CYCLOHEXYL-ACETAMIDE synthesis
- Product Name:2-CYANO-N-CYCLOHEXYL-ACETAMIDE
- CAS Number:15029-38-6
- Molecular formula:C9H14N2O
- Molecular Weight:166.22
108-91-8
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105-56-6
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15029-38-6
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$28.60/50MG
Yield:15029-38-6 90%
Reaction Conditions:
with sodium ethanolate in ethanol at 20; for 1 h;
Steps:
4.2. General procedure 1: synthesis of cyanoacetamides 2a-d
General procedure: A mixture of a solution of sodium ethoxide (0.1 mmol) in ethanol (3 mL), ethyl cyanoacetate (10 mmol) and amine (10 mmol) was stirred at room temperature. The reaction time is 1 h for primary amines and 24 h for secondary amine 2d. The precipitate obtained was separated by filtration, washed with diethylether and recrystallised in ethanol to provide a white solid of cyanoacetamides.
References:
Cheikh, Nawel;Bar, Nathalie;Choukchou-Braham, Nourredine;Mostefa-Kara, Bachir;Lohier, Jean-Franois;Sopkova, Jana;Villemin, Didier [Tetrahedron,2011,vol. 67,# 8,p. 1540 - 1551] Location in patent:experimental part
108-91-8
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372-09-8
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$20.00/25g
15029-38-6
25 suppliers
$28.60/50MG
108-91-8
626 suppliers
$10.00/5mL
36140-83-7
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$23.00/250mg
15029-38-6
25 suppliers
$28.60/50MG
108-91-8
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$10.00/5mL
107-91-5
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$5.00/10g
15029-38-6
25 suppliers
$28.60/50MG
108-91-8
626 suppliers
$10.00/5mL
105-34-0
456 suppliers
$5.00/25g
15029-38-6
25 suppliers
$28.60/50MG