ChemicalBook CAS DataBase List 2-Nitropropane

2-Nitropropane synthesis

15synthesis methods

Product Name:2-Nitropropane
CAS Number:79-46-9
Molecular formula:C3H7NO2
Molecular Weight:89.09

Like 1-nitropropane, 2-nitropropane is produced by vapor-phase nitration of propane with nitric acid at elevated temperature and pressure (Baker and Bollmeier 1978). U.S. production in 1977 was put at 30 million pounds (Finklea 1977). Amounts in use have been greatly reduced in recent times because of concern about its carcinogenic potential.

127-06-0 Synthesis

127-06-0
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79-46-9
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$10.00/5G

Yield:79-46-9 96.5%

Reaction Conditions:

with dihydrogen peroxide;sodium carbonate in methanol at 60; under 750.075 Torr;

Steps:

1

73 g of acetone oxime and 160 g of methanol were mixed by a mixer and equipped with metering pumps A,Hydrogen peroxide (content of 70%) 97g with metering pump B3 g (catalyst ratio of 30 to 30) with V-ZSM-5 catalyst was continuously added,0.003 g of sodium carbonate in a reaction vessel at a temperature of 60 ° C and a pressure of 0.01 MPa.Membrane-separated reaction supernatants were subjected to desolvation to give 85.9 g of 2-nitropropane, the yield was 96.5%Purity of 99.2%, unreacted oxime and solvent recovery after recovery to continue the oxidation reaction,V-ZSM-5 catalyst to give 2.87 g.

References:

CN106631809,2017,A Location in patent:Paragraph 0017; 0018