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ChemicalBook CAS DataBase List 3-AMINO-5-BROMOBENZOATE

3-AMINO-5-BROMOBENZOATE synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: sulfuric acid; N-Bromosuccinimide / 2 h / 60 °C
2: sodium carbonate / N,N-dimethyl-formamide / 8 h / 60 °C
3: ammonium chloride; iron / ethanol; water / 1 h / 80 °C

References:

Kuntz, Kevin W.;Campbell, John E.;Keilhack, Heike;Pollock, Roy M.;Knutson, Sarah K.;Porter-Scott, Margaret;Richon, Victoria M.;Sneeringer, Chris J.;Wigle, Tim J.;Allain, Christina J.;Majer, Christina R.;Moyer, Mikel P.;Copeland, Robert A.;Chesworth, Richard [Journal of Medicinal Chemistry,2016,vol. 59,# 4,p. 1556 - 1564]

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