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ChemicalBook CAS DataBase List 3-Hydroxy-5-phenyl-2-cyclohexen-1-one, 97%
35376-44-4

3-Hydroxy-5-phenyl-2-cyclohexen-1-one, 97% synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: sodium hydroxide / water / 2 h / 65 °C
2.1: sodium methylate / methanol / 4 h / Reflux
2.2: 1 h / 80 °C
2.3: 1 h / Reflux

References:

Dragovich, Peter S.;Fauber, Benjamin P.;Boggs, Jason;Chen, Jinhua;Corson, Laura B.;Ding, Charles Z.;Eigenbrot, Charles;Ge, Hongxiu;Giannetti, Anthony M.;Hunsaker, Thomas;Labadie, Sharada;Li, Chiho;Liu, Yichin;Liu, Yingchun;Ma, Shuguang;Malek, Shiva;Peterson, David;Pitts, Keith E.;Purkey, Hans E.;Robarge, Kirk;Salphati, Laurent;Sideris, Steve;Ultsch, Mark;Vanderporten, Erica;Wang, Jing;Wei, Binqing;Xu, Qing;Yen, Ivana;Yue, Qin;Zhang, Huihui;Zhang, Xuying;Zhou, Aihe [Bioorganic and Medicinal Chemistry Letters,2014,vol. 24,# 16,p. 3764 - 3771]