ChemicalBook CAS DataBase List 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro-1-methyl- (9CI)

7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro-1-methyl- (9CI) synthesis

2synthesis methods

Product Name:7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro-1-methyl- (9CI)
CAS Number:314021-93-7
Molecular formula:C6H6N4O
Molecular Weight:150.14

Methyl 4-aMino-1-Methyl-1h-pyrazole-5-carboxylate

923283-54-9
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$65.00/100mg

3473-63-0 Synthesis

3473-63-0
474 suppliers
$5.00/25g

7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro-1-methyl- (9CI)

314021-93-7
46 suppliers
$305.00/250mg

Yield:314021-93-7 94%

Reaction Conditions:

with N-ethyl-N,N-diisopropylamine in butan-1-ol at 110; for 1 h;

Steps:

4

Compound 8: To a solution of 7 (0.92 g, 5.9 mmol) in 5 mL of Hunig's base and 5 mL of n-butanol was added formamidine acetate (0.68 g, 6.5 mmol). The reaction mixture was heated and stirred at 110° C. for 1 hour. After cooling to room temperature, the white precipitate was collected by filtration and washed with diethyl ether. The resulting white precipitate was dried under reduced pressure to afford 8 (0.83 g, 94%). ¹H NMR (d6-DMSO) δ 4.33 (s, 3H) 8.50 (s, 1H) 8.80 (s, 1H); ES (+) MS m/e=151 (M+1).

References:

US2007/27166,2007,A1 Location in patent:Page/Page column 80

1260659-38-8 Synthesis

Ethyl 4-amino-1-methyl-1h-pyrazole-5-carboxylate

1260659-38-8
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60100-09-6
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314021-93-7
46 suppliers
$305.00/250mg

References

7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro-1-methyl- (9CI) Related Search:

1-Methyl-2-imidazolecarboxaldehyde 1-ETHYL-1-METHYLPYRROLIDINIUM BROMIDE 1-Methyl-1H-pyrrolo[2,3-b]pyridine Imidazole, 1-methyl-4-nitro- 1-Methyl-7-nitro-1,2,3,4-tetrahydroquinoline 1H-Indazol-5-ol, 1-methyl- (9CI) 1-Methyl-1H-imidazole-2-carboxylic acid 1H-Benzimidazole-6-carboxaldehyde, 1-methyl- (9CI)