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Formamidine acetate

CAS No.
3473-63-0
Chemical Name:
Formamidine acetate
Synonyms
FAA;forMiMidaMide acetate;Formamidinium acetate;FORMAMIDINE ACETATE SALT;IMINOFORMAMIDE ACETATE;Methanimidamide(9CI);Methanimidamide monoacetate;FORMAMIDINE ACETIC ACID SALT;CB3408896;ormamidine acetate
CBNumber:
CB3408896
Molecular Formula:
C3H8N2O2
Molecular Weight:
104.11
MDL Number:
MFCD00012866
MOL File:
3473-63-0.mol
MSDS File:
SDS
Last updated:2025-04-11 21:28:41
Product description Number Pack Size Price
Formamidine acetate salt 99% F15803 100g $63.6
Formamidine acetate salt 99% F15803 500g $236
Formamidine acetate for synthesis 8.14653 100g $126
Formamidine acetate for synthesis 8.14653 500g $342
Formamidine Acetate >98.0%(T) F0154 25g $25
More product size

Formamidine acetate Properties

Melting point 158-161 °C (dec.)(lit.)
Density 1.124
storage temp. Store below +30°C.
solubility 832g/l
form Liquid
color Clear colorless to light yellow
PH 8 (400g/l, H2O, 20℃)
Water Solubility 832 g/L (21 ºC)
Sensitive Hygroscopic
BRN 3563488
InChI InChI=1S/C2H4O2.CH4N2/c1-2(3)4;2-1-3/h1H3,(H,3,4);1H,(H3,2,3)
InChIKey XPOLVIIHTDKJRY-UHFFFAOYSA-N
SMILES C(C)(=O)O.C(=N)N
CAS DataBase Reference 3473-63-0(CAS DataBase Reference)
FDA UNII VX3J2EM4N7
EPA Substance Registry System Methanimidamide, monoacetate (3473-63-0)
UNSPSC Code 12352107
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P261-P272-P280-P302+P352-P333+P313-P362+P364
Hazard Codes  Xi
Risk Statements  43-36/37/38
Safety Statements  36/37-37/39-26-36/37/39-27
WGK Germany  2
3-9-21
Autoignition Temperature 565 °C
TSCA  Yes
HS Code  29252000
Toxicity LD50 orally in Rabbit: 2510 mg/kg LD50 dermal Rat > 2000 mg/kg
NFPA 704
0
1 0

Formamidine acetate price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich F15803 Formamidine acetate salt 99% 3473-63-0 100g $63.6 2025-07-31 Buy
Sigma-Aldrich F15803 Formamidine acetate salt 99% 3473-63-0 500g $236 2025-07-31 Buy
Sigma-Aldrich 8.14653 Formamidine acetate for synthesis 3473-63-0 100g $126 2025-07-31 Buy
Sigma-Aldrich 8.14653 Formamidine acetate for synthesis 3473-63-0 500g $342 2025-07-31 Buy
TCI Chemical F0154 Formamidine Acetate >98.0%(T) 3473-63-0 25g $25 2025-07-31 Buy
Product number Packaging Price Buy
F15803 100g $63.6 Buy
F15803 500g $236 Buy
8.14653 100g $126 Buy
8.14653 500g $342 Buy
F0154 25g $25 Buy

Formamidine acetate Chemical Properties,Uses,Production

Description

Formamidine acetate is an anti-tuberculosis drug that belongs to the class of aminoglycosides. It has been shown to have a potent cytotoxic effect on malignant brain cells in vitro. It inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. It also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

Chemical Properties

white to light yellow crystalline powder

Uses

Formamidine acetate salt is widely used in the preparation of formamidinium lead triiodide (FAPbI3) perovskites for perovskite solar cells. It is also used in the synthesis of formamidinium lead bromide nanocrystals for use as emitters in display applications.

Uses

Formamidine acetate is used as an intermediate in the synthesis of active pharmaceutical ingredients. It is also used as a condensing agent for the preparation of pyrimidine and imidazole heterocycles.

Purification Methods

Unlike the hydrochloride, the acetate salt is not hygroscopic. It is recrystallised from a small volume of acetic acid, by addition of EtOH and the crystals are washed with EtOH then Et2O and dried in a vacuum. [Taylor et al. Org Synth 46 39 1966, Beilstein 2 IV 82.]

64-19-7
122-51-0
3473-63-0
Synthesis of Formamidine acetate from Acetic acid and Triethyl orthoformate
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View Lastest Price from Formamidine acetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Formamidine acetate pictures 2025-11-13 Formamidine acetate
3473-63-0
US $45.00-230.00 / g 25g 0.98 100kg Shanghai UCHEM Inc.
Formamidine acetate pictures 2025-11-12 Formamidine acetate
3473-63-0
US $5.50 / kg 1kg 0.99 100tons HANGZHOU HAILAN CHEMICAL CO.,LTD.
Formamidine acetate pictures 2025-11-10 Formamidine acetate
3473-63-0
US $1.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
FORMAMIDINE,ACETIC ACID FORMAMIDINE ACETATE Methanimidamideacetate formamidine monoacetate Formamidineacetate,99% Formamidinmonoacetat Acetic acid·formamidine ForMaMidine acetate salt 99% Acetic acid arMour aMidine Imidoformamide acetate ForMaMidine acetate, 99% 100GR ForMaMidine acetate, 99% 5GR FORMAMIDINE ACETATE FOR SYNTHESIS ormamidine acetate FormamidineAcetate> FormaFormamidine acetatemidine acetate Acetic acid armour am High quality Formamidine acetate CAS 3473-63-0 methanimidoylazanium IMINOFORMAMIDE ACETATE FORMAMIDINE ACETATE SALT FORMAMIDINE ACETIC ACID SALT FAA forMiMidaMide acetate Methanimidamide(9CI) Methanimidamide monoacetate Formamidinium acetate Formamidine acetate (6CI) CB3408896 Methylamidine acetate 3473-63-0 40730-91-7 HNCHNH2CH3COOH CH4N2CH3COOH CH4N2C2H4O2 C2H4O2CH4N2 Imines/Amidines Nitrogen Compounds Organic Building Blocks Building Blocks API Pharmaceutical Intermediates bc0001 3473-63-0