ChemicalBook CAS DataBase List 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine synthesis

13synthesis methods

Product Name:3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
CAS Number:329214-79-1
Molecular formula:C11H16BNO2
Molecular Weight:205.06

626-55-1 Synthesis

626-55-1
581 suppliers
$5.00/5 / G

73183-34-3
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$6.00/5g

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

329214-79-1
245 suppliers
$6.00/1g

Yield:329214-79-1 95%

Reaction Conditions:

with PdCl₂(dppf);potassium acetate in toluene at 100; for 3 h;

Steps:

I.2.3; I.5.3; I.6.4; III.12.3 Core side 1-I-2 Synthesis
3-Bromopyridine (130 g, 822.8 mmol)(250.73 g, 987.3 mmol) and 4,4,4 ', 4', 5,5,5 ', 5'-octamethyl-2,2'-bi (1,3,2-dioxaborolane) and PdCl2 (20.16 g, 24.7 mmol)And potassium acetate (242.24 g, 2,468.4 mmol) was added to a round bottom flask,Toluene (4,000 mL)And the mixture was stirred at 100 ° C for 3 hours.When the reaction is terminated, the reaction product is quenched by adding water, and water in the reaction product is removed. After filtration under reduced pressure,The organic layer was dried over MgSO4 and concentrated to give 160.28 g (yield: 95%) of the product.

References:

Duksan Neolux Co.,Ltd.;Yoon Jin-ho;Jeong Ho-yeong;Park Mu-jin;Kim Jeong-seok;Lee Seon-hui KR2018/128292, 2018, A Location in patent:Page/Page column 22; 23; 25; 26; 40

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626-60-8 Synthesis