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3400-90-6

4-CYCLOPENTYL-4-OXO-BUTYRIC ACID synthesis

6synthesis methods
-

Yield:-

Reaction Conditions:

Stage #1: Cyclopentyl bromidewith magnesium in diethyl ether;Reflux;
Stage #2: succinic acid anhydridewith iron(III)-acetylacetonate in tetrahydrofuran at 0;

References:

Guijarro, David;Pablo, Oscar;Yus, Miguel [Journal of Organic Chemistry,2013,vol. 78,# 8,p. 3647 - 3654]