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3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER

CAS No.
24922-00-7
Chemical Name:
3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER
Synonyms
Cyclopentanepropanoicacid, b-oxo;ETHYL 3-CYCLOPENTYL-3-OXOPROPANOATE;Ethyl 3-cyclopentyl-3-oxopropionate;Cyclopentanepropanoicacid, b-oxo-, ethyl ester;3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER;Cyclopentanepropanoic acid, β-oxo-, ethyl ester
CBNumber:
CB6234007
Molecular Formula:
C10H16O3
Molecular Weight:
184.23
MDL Number:
MFCD06410650
MOL File:
24922-00-7.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:47
Product description Number Pack Size Price
Ethyl3-Cyclopentyl-3-oxopropanoate E926825 50mg $45
3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER 95.00% CHM0129381 5G $1443.17
3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER 95.00% CHM0129381 10G $2328.48
Ethyl 3-cyclopentyl-3-oxopropionate 2229-1-76 25g $2496
Ethyl3-cyclopentyl-3-oxopropanoate 97% A162189 250mg $22
More product size

3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER Properties

Boiling point 91-94 °C(Press: 1.8 Torr)
Density 1.065±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 10.51±0.20(Predicted)
Appearance Colorless to light yellow Liquid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301+H311+H331-H412-H227
Precautionary statements  P501-P261-P273-P270-P210-P271-P264-P280-P370+P378-P361+P364-P301+P310+P330-P302+P352+P312-P304+P340+P311-P403+P233-P403+P235-P405
HS Code  2918999090

3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC E926825 Ethyl3-Cyclopentyl-3-oxopropanoate 24922-00-7 50mg $45 2021-12-16 Buy
American Custom Chemicals Corporation CHM0129381 3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER 95.00% 24922-00-7 5G $1443.17 2021-12-16 Buy
American Custom Chemicals Corporation CHM0129381 3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER 95.00% 24922-00-7 10G $2328.48 2021-12-16 Buy
SynQuest Laboratories 2229-1-76 Ethyl 3-cyclopentyl-3-oxopropionate 24922-00-7 25g $2496 2021-12-16 Buy
Ambeed A162189 Ethyl3-cyclopentyl-3-oxopropanoate 97% 24922-00-7 250mg $22 2021-12-16 Buy
Product number Packaging Price Buy
E926825 50mg $45 Buy
CHM0129381 5G $1443.17 Buy
CHM0129381 10G $2328.48 Buy
2229-1-76 25g $2496 Buy
A162189 250mg $22 Buy

3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER Chemical Properties,Uses,Production

Uses

Ethyl 3-cyclopentyl-3-oxopropionate can be used as a pharmaceutical synthesis intermediate.

Synthesis

Cyclopentanecarbonyl chloride

4524-93-0

3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER

24922-00-7

6a) A hexane solution of 2.4 M n-butyllithium (92.0 mL, 230 mmol) was slowly added dropwise to a solution containing monoethyl malonate (13.6 mL, 115 mmol) and a catalytic amount of 2,2'-bipyridine at -55 to -65 °C. After the dropwise addition, cyclopentanecarbonyl chloride (7.0 mL, 58 mmol) was added in batches. The reaction mixture was gradually warmed to room temperature with stirring and subsequently poured into a mixture of 1N aqueous hydrochloric acid solution and ether. The organic layer was separated, washed three times with saturated sodium bicarbonate solution, dried over anhydrous magnesium sulfate, concentrated and then purified by silica gel column chromatography (eluent: 0-5% ethyl acetate in hexane solution with gradient elution) to afford ethyl 3-cyclopentyl-3-oxopropanoate (9.50 g, 89% yield).1H-NMR (400 MHz, DMSO-d6) δ 4.06 (q, J = 7 Hz. 2H), 3.60 (s, 2H), 2.99-2.91 (m, 1H), 1.78-1.47 (m, 8H), 1.15 (t, J = 7 Hz, 3H).

References

[1] Patent: US2008/96921, 2008, A1. Location in patent: Page/Page column 42
[2] Journal of Medicinal Chemistry, 1998, vol. 41, # 17, p. 3186 - 3201

4524-93-0
24922-00-7
Synthesis of 3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER from Cyclopentanecarbonyl chloride
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View Lastest Price from 3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER pictures 2020-01-13 3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER
24922-00-7
US $0.01 / KG 1KG 98%; 99% 500g; 1kg; 25kg Career Henan Chemical Co
3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER pictures 2019-12-23 3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER
24922-00-7
US $1.00 / g 1g 99% 1000KGS Career Henan Chemical Co

3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER Spectrum

ETHYL 3-CYCLOPENTYL-3-OXOPROPANOATE 3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER Ethyl 3-cyclopentyl-3-oxopropionate Cyclopentanepropanoicacid, b-oxo-, ethyl ester Cyclopentanepropanoicacid, b-oxo Cyclopentanepropanoic acid, β-oxo-, ethyl ester 24922-00-7