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4-ethoxypropiophenone synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 3 h / 20 °C / Inert atmosphere
1.2: 0 °C / Inert atmosphere
2.1: tetrahydrofuran / 0 - 20 °C / Inert atmosphere

References:

Komatsuda, Masaaki;Kondo, Hiroki;Ohki, Hugo;Suto, Ayane;Yamaguchi, Junichiro [Organic Letters,2022,vol. 24,# 17,p. 3270 - 3274]

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