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ChemicalBook CAS DataBase List (4-METHOXY-BENZYL)-TRIMETHYL-SILANE
17988-20-4

(4-METHOXY-BENZYL)-TRIMETHYL-SILANE synthesis

12synthesis methods
-

Yield:17988-20-4 98%

Reaction Conditions:

Stage #1: 1-bromo-4-methoxy-benzenewith bis(tri-t-butylphosphine)palladium(0);oxygen in toluene at 20; for 0.0166667 h;Schlenk technique;
Stage #2: trimethylsilylmethyllithium in toluene at 20; for 0.0333333 h;Schlenk technique;

References:

Heijnen, Dorus;Tosi, Filippo;Vila, Carlos;Stuart, Marc C. A.;Elsinga, Philip H.;Szymanski, Wiktor;Feringa, Ben L. [Angewandte Chemie - International Edition,2017,vol. 56,# 12,p. 3354 - 3359][Angew. Chem.,2017,vol. 129,# 12,p. 3402 - 3407,6] Location in patent:supporting information

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