4-Methylcyclohexanone synthesis
- Product Name:4-Methylcyclohexanone
- CAS Number:589-92-4
- Molecular formula:C7H12O
- Molecular Weight:112.17
589-91-3
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$10.00/5mL
589-92-4
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$6.00/5g
Yield:589-92-4 98.1%
Reaction Conditions:
with hydrogenchloride;2,2,6,6-Tetramethyl-1-piperidinyloxy free radical;oxygen;NaNO2 in lithium hydroxide monohydrate at 45; under 7500.75 Torr; for 0.5 h;Autoclave;Solvent;
Steps:
1; 5 Example 1 (synthesis of 4-methylcyclohexanone)
11.4g of 4-methylcyclohexanol was added to a 500mL autoclave, dissolved in 200mL of perfluorodecalin, then 0.16g of catalyst TEMPO (shown in formula 1), 1mL of hydrochloric acid (20wt% solution), 0.07g Sodium nitrate, then maintained 1MPa oxygen continued to feed, and stirred at 45 ° C for 0.5 hours, washed with water after the reaction, and then separated the organic phase, dried with anhydrous sodium sulfate overnight, and distilled to remove the organic solvent to obtain 11.0g of colorless liquid 4 - Methylcyclohexanone, yield 98.1%.
References:
CN114671746,2022,A Location in patent:Paragraph 0028-0030; 0040-0042
106-44-5
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$14.00/5g
589-92-4
250 suppliers
$6.00/5g
7731-28-4
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$40.00/1mL
589-92-4
250 suppliers
$6.00/5g
106-44-5
455 suppliers
$14.00/5g
589-91-3
172 suppliers
$10.00/5mL
589-92-4
250 suppliers
$6.00/5g
108-88-3
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