Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
logo
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook

Welcome back!

Structured search
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
ChemicalBook CAS DataBase List 5-BROMO-2-HYDROXYBENZONITRILE
40530-18-5

5-BROMO-2-HYDROXYBENZONITRILE synthesis

11synthesis methods
5-Bromosalicylaldehyde

1761-61-1
389 suppliers
$5.00/5g

5-BROMO-2-HYDROXYBENZONITRILE

40530-18-5
183 suppliers
$15.00/1g

-

Yield:40530-18-5 95%

Reaction Conditions:

with formic acid;hydroxylamine hydrochloride;sodium formate at 100; for 7 h;

Steps:

1

5-Bromo-2-hydroxybenzonitrile; To a solution of 5-bromosalicylaldehyde (80.0 g, 0.40 mol) in formic acid were added hydroxylamine hydrochloride (36.0 g, 0.52 mol) and sodium format (37.0 g, 0.52 mol) followed by stirring at 100°C for 7 hours. Ethyl acetate was added to the residue prepared by evaporation of the solvent, the mixture was washed with water and then an organic layer was dried. Petroleum ether was added to the residue prepared by evaporation of the solvent and the crystals separated out therefrom were filtered to give the title compound (75.2 g, 95%). 1H-NMR (DMSO-d6) δ: 6.98 (d, J=8.9 Hz, 1H), 7.65 (dd, J=8.9, 2.4 Hz, 1H), 7.86 (d, J=2.4 Hz, 1H), 11.41 (s, 1H).

References:

EP2128136,2009,A1 Location in patent:Page/Page column 7

5-Bromo-2-methoxybenzonitrile

144649-99-0
128 suppliers
$6.00/250mg

5-BROMO-2-HYDROXYBENZONITRILE

40530-18-5
183 suppliers
$15.00/1g

References
82486-43-9 Synthesis
5-BROMO-2-HYDROXYBENZALDEHYDE OXIME

82486-43-9
17 suppliers
$45.00/250mg

5-BROMO-2-HYDROXYBENZONITRILE

40530-18-5
183 suppliers
$15.00/1g

References
50-00-0 Synthesis
Formaldehyde

50-00-0
895 suppliers
$10.00/25g

4-Bromophenol

106-41-2
501 suppliers
$13.00/5g

5-BROMO-2-HYDROXYBENZONITRILE

40530-18-5
183 suppliers
$15.00/1g

References
4-BROMO-2-METHYLANISOLE

14804-31-0
161 suppliers
$7.00/5g

5-BROMO-2-HYDROXYBENZONITRILE

40530-18-5
183 suppliers
$15.00/1g

References

5-BROMO-2-HYDROXYBENZONITRILE Related Search:

5-BROMO-2-ISOPROPOXY-BENZONITRILE 4-BROMO-2-HYDROXYBENZONITRILE 3-BROMO-4-HYDROXYBENZONITRILE Bromoxynil 2-Cyanophenol 3,5-DIBROMO-2-HYDROXYBENZONITRILE