6-iodo-N,N-diMethylbenzo[d][1,3]dioxol-5-aMine synthesis
- Product Name:6-iodo-N,N-diMethylbenzo[d][1,3]dioxol-5-aMine
- CAS Number:1061318-82-8
- Molecular formula:C9H10INO2
- Molecular Weight:291.09
14268-66-7
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$20.00/5G
1061318-82-8
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13067-19-1
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$45.00/10mg
Yield:13067-19-1 95%
Reaction Conditions:
with acetic anhydride in acetic acid;
Steps:
7.a Step 7a.
Step 7a. 6-Iodo-N,N-dimethylbenzo[d][1,3]dioxol-5-amine (Compound 0102-15) To a solution of 3,4-(Methylenedioxy)aniline (8 g, 58.3 mmol) in AcOH (120 ml) was added Ac2O (48 mL). The mixture was stirred for overnight. After reaction, the mixture was poured into saturated NaHCO3 solution, and then filtered. The filtrate was extracted with ethyl acetate to give N-(benzo[d][1,3]dioxol-5-yl)acetamide (10 g, 95%). LCMS: 180[M+1]+; 1H NMR (DMSO-d6) δ 2.0 (s, 3H), 5.96 (s, 2H), 6.82 (d, 1H, J=8.1 Hz), 6.91 (d, 1H, J=2.1 Hz), 7.30 (d, 1H, J=1.8 Hz), 9.84 (s, 1H).
References:
US2010/184801,2010,A1
50-00-0
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1000802-34-5
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$57.00/100mg
1061318-82-8
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