ChemicalBook CAS DataBase List 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one synthesis

5synthesis methods

Product Name:1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one
CAS Number:62780-89-6
Molecular formula:C10H11ClN2O
Molecular Weight:210.66

62780-84-1 Synthesis

1-(3-chloropropyl)-1,3-dihydro-3-(1-methylvinyl)-2H-benzimidazol-2-one

62780-84-1
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1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

62780-89-6
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$39.00/1g

Yield:62780-89-6 92%

Reaction Conditions:

with phosphoric acid;propiononitrile at 75; for 4 h;Concentration;Temperature;

Steps:

3.2
(Ii) in the above-mentioned oily (3) the mass fraction of added in 40% phosphoric acid solution 120 ml, the mass fraction of 80% third eyeball 60 ml, control the stirring speed 130rpm, raising the temperature of the solution to 75 °C, reaction 4h, evaporate portion third eyeball, cooling, separating solid, filtering, washing the solid with the potassium chloride solution, anhydrous potassium carbonate dehydration, to obtain 1 - (3-chloro-propyl)-benzimidazole-2-one 36.88g, yield 92%.

References:

Chengdu Cardiff Science and Techn Co., Ltd;Liao, Ruer CN105439960, 2016, A Location in patent:Paragraph 0008; 0020

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