Benzoic Acid, 4-(2-Carboxyethoxy)-, 1-Methyl Ester(WX610223) synthesis
- Product Name:Benzoic Acid, 4-(2-Carboxyethoxy)-, 1-Methyl Ester(WX610223)
- CAS Number:72155-09-0
- Molecular formula:C11H12O5
- Molecular Weight:224.21
57-57-8
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99-76-3
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72155-09-0
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Yield:72155-09-0 52%
Reaction Conditions:
Stage #1: methyl 4-hydroxylbenzoatewith sodium hydroxide in water at 80;
Stage #2: β-Propiolactone in water at 80; for 0.5 h;
References:
Golani, Lalit K.;Wallace-Povirk, Adrianne;Deis, Siobhan M.;Wong, Jennifer;Ke, Jiyuan;Gu, Xin;Raghavan, Sudhir;Wilson, Mike R.;Li, Xinxin;Polin, Lisa;De Waal, Parker W.;White, Kathryn;Kushner, Juiwanna;O'Connor, Carrie;Hou, Zhanjun;Xu, H. Eric;Melcher, Karsten;Dann, Charles E.;Matherly, Larry H.;Gangjee, Aleem [Journal of Medicinal Chemistry,2016,vol. 59,# 17,p. 7856 - 7876]
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72155-09-0
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72155-20-5
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72155-09-0
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72155-09-0
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