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ChemicalBook CAS DataBase List (2S,4R)-4-hydroxy-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid tert-butyl ester
72289-52-2

(2S,4R)-4-hydroxy-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid tert-butyl ester synthesis

9synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: aq. NaOH / 20 h / 20 °C
2: 6.0 g / 6 h / 80 °C

References:

Sugase, Kenji;Horikawa, Manabu;Sugiyama, Masako;Ishiguro, Masaji [Journal of Medicinal Chemistry,2004,vol. 47,# 2,p. 489 - 492]

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(2S,4R)-4-hydroxy-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid tert-butyl ester

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