Cinnamyl bromide synthesis
- Product Name:Cinnamyl bromide
- CAS Number:4392-24-9
- Molecular formula:C9H9Br
- Molecular Weight:197.07
4407-36-7
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4392-24-9
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Yield:4392-24-9 96.2%
Reaction Conditions:
with phosphorus tribromide in dichloromethane for 1 h;
Steps:
1.III 1. Synthesis Process I
Step (III):
To a 100 ml round bottom flask was added 3-phenyl-pro-2-pen-1-ol (D011c, 1 g, 7.45 mmol, 1 eq), was dissolved in anhydrous dichloromethane, PBr3 (phosphoric tribromide, 253.6 μl, 2.608 mmol, 0.35 eq) was added on the steam bath and stirred for 1 hour.
The reaction mixture was concentrated and purified by silica gel column chromatography (ethyl acetate:n-hexane=1:8) to obtain the pure product, 3-bromo-propenyl)-benzene (D005d, 1.42 g, yield=96.2%, Rf=0.34 (5:1 n-hexane-ethyl acetate) which was applied to the next step.
References:
PRG S&TECH INC.;PARK, Bum Joon;SONG, Gyu Yong;O, Yu Seok;LEE, Jee Hyun;YUN, Eun Ju US2020/48274, 2020, A1 Location in patent:Paragraph 0056-0057
104-54-1
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4392-24-9
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4393-06-0
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4392-24-9
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300-57-2
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4392-24-9
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![Benzene, [3-(methoxymethoxy)-1-propen-1-yl]-](/CAS/20200611/GIF/91970-13-7.gif)
91970-13-7
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4392-24-9
181 suppliers
$18.00/5g