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ChemicalBook CAS DataBase List Crotonamide
625-37-6

Crotonamide synthesis

8synthesis methods
-

Yield:625-37-6 80%

Reaction Conditions:

with Acetaldehyde oxime;[(eta.(5)-pentamethylcyclopentadienyl)Rh(H2O)3](OTf)2 in water;Schlenk technique;

Steps:

19 Example 19: 2-Butenamide

2-Butenenitrile (67 mg, 1 mmol), [Cp * Rh (H,2O)3] [OTf]2(3.0 mg, 0.005 mmol, 0.5 mol%), acetaldehyde oxime (65 mg, 1.1 mmol) and water (1 ml) were successively added to a 25 ml Schlenk reaction flask and the water was removed by rotary evaporation to give the desired product. Yield: 80%

References:

CN104744288,2017,B Location in patent:Paragraph 0097; 0098; 0099; 0100