ChemicalBook CAS DataBase List Cyclohexanecarboxylic acid chloride

Cyclohexanecarboxylic acid chloride synthesis

9synthesis methods

Product Name:Cyclohexanecarboxylic acid chloride
CAS Number:2719-27-9
Molecular formula:C7H11ClO
Molecular Weight:146.61

98-89-5 Synthesis

98-89-5
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$13.00/25g

2719-27-9
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$16.00/25mL

Yield:2719-27-9 99%

Reaction Conditions:

with thionyl chloride in dodecane;benzene at 20; for 1 h;Heating / reflux;

Steps:

1.ii EXAMPLE 1
20.0 g (cyclohexanecarboxylic acid: 6.95 g, 0.054 mol) of the cyclohexanecarboxylic acid solution and 1.0 g of n-dodecane as an internal standard material were added to a reactor equipped with a condenser and a Dean-Stark water separator. After adding 90 ml of benzene, about 25 ml of benzene was distilled off in the nitrogen atmosphere to make the anhydrous solution. The temperature of the reactant solution was lowered to the atmospheric temperature and 6.0 ml (9.8 g, 0.082 mol) of thionyl chloride was added for one hour of reflux. [0046] After the reaction, part of the reactant solution was collected and reacted with methanol including a small amount of triethylamine in order to identify the product, cyclohexanecarbonyl chloride. The yield of methyl cyclohexane carboxylate was analyzed by GC. As a result, cyclohexanecarbonyl chloride was produced with a conversion rate of more than 99% and a selectivity of more than 99%.

References:

Korea Kumho Petrochemical Co., Ltd. US2004/73068, 2004, A1 Location in patent:Page 3

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2043-61-0 Synthesis