diethyl 4-(trifluoroMethyl)benzylphosphonate synthesis
- Product Name:diethyl 4-(trifluoroMethyl)benzylphosphonate
- CAS Number:99578-68-4
- Molecular formula:C12H16F3O3P
- Molecular Weight:296.22
Yield:99578-68-4 95%
Reaction Conditions:
Stage #1: phosphonic acid diethyl esterwith sodium hydride in N,N-dimethyl-formamide; for 0.5 h;Cooling with ice;Inert atmosphere;
Stage #2: 4-bromomethyltrifluoromethylbenzene in N,N-dimethyl-formamide at 20; for 8.5 h;Inert atmosphere;
References:
Huang, Tianzeng;Chen, Tieqiao;Han, Li-Biao [Journal of Organic Chemistry,2018,vol. 83,# 5,p. 2959 - 2965]
402-49-3
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99578-68-4
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455-19-6
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99578-68-4
25 suppliers
$60.29/1g